E. , Pronin A. N. , Benovic J. L. and Wedegaertner P. B. ( 2003 ) G protein-coupled receptor kinase 2/Gα q/11 interaction. A novel surface on a regulator of G protein signaling homology domain for binding Gα-subunits . J. Biol. Chem. 278 , 6050 – 6058 ....
G protein-coupled receptor kinase 2 (GRK2) is a key modulator of G protein-coupled receptors and other plasma membrane receptors stimulated by chemotactic messengers. On top of that, GRK2 has been reported to interact with a variety of signal transduction proteins related to cell migration such...
G-protein-coupled receptor kinase 2 (GRK2) is arising as one of such nodes. Via its complex network of connections with other cellular proteins, GRK2 contributes to the modulation of basic cellular functions-such as cell proliferation, survival, or motility-and is involved in metabolic ...
G protein-coupled receptor kinase 2 (GRK2) is a serine/threonine-specific protein kinase that mediates agonist-dependent phosphorylation of numerous G protein-coupled receptors. In an effort to identify proteins that regulate GRK2 function, we searched for interacting proteins by immunoprecipitation of...
上海玉博生物科技有限公司 主要致力于“Anti-GRK2 (G-protein coupled receptor kinase 2) G蛋白偶合受体激酶2抗体 yb-1209R”的生产销售。多年的“Anti-GRK2 (G-protein coupled receptor kinase 2) G蛋白偶合受体激酶2抗体 yb-1209R”生产与销售的经验,与各行业新老用
L. G. Protein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation. J. Biol. Chem. 278, 50908–50914 (2003). CAS PubMed Google Scholar Chen, M. et al. Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via ...
Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells. (2000). Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic sm...
G protein-coupled receptors;G protein-coupled receptor kinase 2;activity regulation;expression regulation;cancerG 蛋白偶联受体(G protein-coupled receptors,GPCRs)是种类最多的一类受体超家族,它们具有 7次跨膜螺旋结构特征,介导多种配体信号,包括神经递质、激素、气体及其他小分子,是多种药物作用的靶点[1] 。
G protein-coupled receptor kinase 2 (Gprk2/GRK2) plays a conserved role in modulating Hedgehog (Hh) pathway activity, but its mechanism of action remains u... Yongbin,Chen,Shuang,... - 《Genes & Development》 被引量: 107发表: 2010年 G-Protein–coupled receptor kinase expression in hypert...
β1-Adrenergic receptor (β1AR) shows the resistance to agonist-induced internalization. However, β1AR can internalize as G protein-coupled receptor kinase 2 (GRK2) is fused to its carboxyl terminus. Internalization of the β1AR and GRK2 fusion protein (β1AR/GRK2) is dependent on ...