Let me bust some of the many myths surrounding these newly-in-the-zeitgeist-but-not-new medicines. Myth 1: People shouldn’t be using drugs like Ozempic and Mounjaro for weight loss alone. Obesity is a chronic disease. It has been classified as such since the 1990s, owing to the...
Drugs such as GLP-1 agonists can also aid weight loss, but most of them have to be injected, and they are unaffordable for many people. According to Srinivasan, the MIT capsules could be manufactured at a cost that would make them available to people who don’t have access to ...
Drugs for Weight Loss and Maintenance: Present and FutureMany patients achieve desired weight loss by changing their lifestyle. However, if not successful, they have the secondary option of obesity pharmacotherapy. Currently there are three drugs approved......
If all the obese people in Germany (19% of the population) were to be supplied with Wegovy injections at the current price, this would amount to over € 50 billion. This is more than the total expenditure for all prescription drugs covered by public health insurance in 2022 (totalling ...
Weight-loss drugs in development include molecules intended to reduce the absorption of lipids from the GI tract, various ways to limit food intake, and compounds that increase energy expenditure or reduce adipose tissue size. A number of new preparations, including combinations of the existing ...
The long-term effects on weight have only been studied for orlistat and sibutramine. The net effects of these drugs vary between 2-5% loss of weight after 1-2 years of treatment. However, the effects of orlistat and sibutramine on morbidity and mortality have not been studied extensively. In...
As all the effects of IFNs are mediated through ISGs, understanding of the function of these genes might lead to more efficacious antiviral and anti-cancer drugs. Abstract The family of interferon (IFN) proteins has now more than reached the potential envisioned by early discovering virologists:...
Accumulation of amyloid-β (Aβ) peptides is considered one of the fundamental neuropathological pillars of AD. • Most experimental drugs that target Aβ pathology have not been able to significantly reduce the progress of AD and memory impairment. • Early detection, Aβ oligomers treatment...
Here, we discuss these new and future heart failure drugs. We explain their mechanisms of action, critically evaluate their performance in clinical trials and summarize the clinical scenarios in which the latest guidelines recommend their use. This Review aims to offer clinicians and researchers a ...
the number of unnecessary and repeat biopsies performed. Chemotherapy, radiotherapy, and prostatectomy are standard treatment options. However, newer novel hormone therapy drugs with a better response have been identified. Androgen deprivation and hormonal therapy are evolving as new and better options ...