b Crystal structure of the trimeric ectodomain of Fsx1. The three-fold non-crystallographic axis is indicated. Subunit A is shown as a cartoon colored by domain, with disulfides and the fusion loop (FL) colored magenta and orange, respectively; subunits B, C are in mixed cartoon/surface ...
More recently it was shown that myoblast fusion requires two unrelated proteins to form muscles in vertebrates7,8. However, many fusogens have not been identi- fied yet, and the molecular basis of gamete fusion in fungi and vertebrates remain unclear9. The first eukaryotic cell–cell fusogen ...