Fused ring compoundsProvided are fused ring compounds of Formula (I), Formula (II), or Formula (III), as further detailed herein, which are used for the inhibition of Ras proteins, as well as compositions comprising these compounds and methods treatment by their administration.LU Aijun...
Fused ring compounds substituted with a 8-azabicyclo[3.2.1]octane(cyclo)alkylene group, including benzothiazolones, e.g., 3-[3-(3-Propyl-8-aza-bicyclo[3.2.1]oct-8-yl)-propyl]-3H-benzothiazol-2-one; highly selective muscarinic agonists, particularly for the M1 and/or M4 receptor subtypes...
All the fused-ring compounds have additional heteroatoms in the ring system. Diels–Alder reactions of two-coordinate intermediates have been utilized to good effect. Thus the arsine (166), used as a dienophile with 2,3-dimethylbutadiene, gave 93% of the arsoxabicyclo[4,3,0]nonane (167) ...
The present invention relates to pyran-fused ring compounds, preparation methods thereof and use thereof, especially to pyran-fused ring compounds usable for preparing Halichondrin, Eribulin, or analogues thereof, preparation methods thereof and use thereof. Use of any of the compounds of formula (...
ame and use thereof Fused ring compounds, process for producing same and use thereofFused ring compounds, process for producing same and use thereofdoi:CN1251577 ACN青野哲也伊藤文雄加来智弘山冈万寿夫
Conformation and reactivity of medium-sized ring compounds. Pure Appl. Chem. 6, 545–560 (1963). Article CAS Google Scholar Burevschi, E., Peña, I. & Sanz, M. E. Medium-sized rings: conformational preferences in cyclooctanone driven by transannular repulsive interactions. Phys. Chem. ...
Fig.10 Separation of basic and polar compounds on Fused-Core columns 如下图11所示,2.6 um的EVO C18色谱柱,在同等长度的条件下,可以获得相近的柱效,峰形也得到改善,与此同时,压力却不到1.7 um的BEHC18色谱柱的一半。 Fig.11 Comparison between BEH ...
Over the past century, the search for lead-free, environmentally friendly initiating substances has been a highly challenging task in the field of energetic materials. Here, an organic primary explosive featuring a fused-ring structure, 6-nitro-7-azido-p
1. A therapeutic agent for hepatitis C, which comprises a fused ring compound of the following formula [I] or a pharmaceutically acceptable salt thereof as an active ingredient: wherein a broken line is a single bond or a double bond, G1 is C(—R1) or a nitrogen atom, G2 is C(—...
AB Deyanov,ME Konshin - 《Chemistry of Heterocyclic Compounds》 被引量: 0发表: 2004年 Catalyst and method for amide formation The invention is a catalyst, the use of the catalyst and a method of using the catalyst in the formation of a compound with an amide bond. The catalyst is an HOB...