The acute toxicity of LASIX has been determined in mice, rats and dogs. In all three, the oral LD50 exceeded 1000 mg/kg body weight, while the intravenous LD50 ranged from 300 to 680 mg/kg. The acute intragastric toxicity in neonatal rats is 7 to 10 times that of adult rats. The con...
The acute toxicity of Furosemide has been determined in mice, rats and dogs. In all three, the oral LD50exceeded 1000 mg/kg body weight, while the intravenous LD50ranged from 300 to 680 mg/kg. The acute intragastric toxicity inneonatalrats is 7 to 10 times that of adult rats. The concen...
The acute toxicity of furosemide has been determined in mice, rats and dogs. In all three, the oral LD50 exceeded 1000 mg/kg body weight, while the intravenous LD50 ranged from 300 to 680 mg/kg. The acute intragastric toxicity in neonatal rats is 7 to 10 times that of adult rats. The...
The acute toxicity of furosemide has been determined in mice, rats and dogs. In all three, the oral LD50 exceeded 1000 mg/kg body weight, while the intravenous LD50 ranged from 300 to 680 mg/kg. The acute intragastric toxicity in neonatal rats is 7 to 10 times that of adult rats. The...
The acute toxicity of Furosemide has been determined in mice, rats and dogs. In all three, the oral LD50exceeded 1000 mg/kg body weight, while the intravenous LD50 ranged from 300 to 680 mg/kg. The acute intragastric toxicity in neonatal rats is 7 to 10 times that of adult rats. ...
Cl (L/kg) 40 45 21 14 17 AUCN (μM h kg/mg) 0.34 0.84 0.79 2.1 1.4 Half-life (h) 0.62 0.44 1.5 1.0 0.85 Fpo (%) 33 38 46 82 65 Table 11. Pharmacokinetics of compounds 51 and 53 in dogs and rhesus monkeys (iv/po doses 1 and 2 mg/kg) Empty Cell5153 DogRhesusDogRhesus...
SC furosemide was initially tested in seven healthy adult mongrel dogs. In a prospective randomized crossover study, SC administration was associated with comparable urine output as oral or intravenous administration (calculated total dose of 2 mg/kg). The peak urine output at 1 h was higher in...
The acute toxicity of LASIX has been determined in mice, rats and dogs. In all three, the oral LD50 exceeded 1000 mg/kg body weight, while the intravenous LD50 ranged from 300 to 680 mg/kg. The acute intragastric toxicity inneonatalrats is 7 to 10 times that of adult rats. ...
Furosemide may cause serious side effects including: increased urination, thirst, muscle cramps, itching, rash, weakness, dizziness, spinning sensation (vertigo), diarrhea, stomach pain, and constipation Dosage for Furosemide The usual initial dose of furosemide is 20 to 40 mg given as a single do...