Latter feature, in combination with the promiscuity of the modifying enzymes and the genetic encoding of the peptide sequence, makes RiPP biosynthetic pathways attractive for synthetic biology approaches to identify novel peptide therapeutics via screening of de novo generated peptide libraries and, thus,...
Discovery of novel fungal RiPP biosynthetic pathways and their application for the development of peptide therapeutics 来自 EBSCO 喜欢 0 阅读量: 36 作者:V Eva,K Markus 摘要: Bioactive peptide natural products are an important source of therapeutics. Prominent examples are the antibiotic penicillin and...