Fungal MDR outbreak: Candida aurisNosanchuk, JoshNosanchuk, Josh
The rise in antimicrobial resistance has become a major threat to public health1. Although the focus has primarily been on pan-resistant bacteria, there is growing concern over the multidrug-resistant fungal pathogen,Candida auris. This emerging pathogen has galvanized researchers, health care workers,...
This translational mouse model of skin colonization and evaluation of infection control measures could be adapted for other MDR microbes, such as Gram-negative and Gram-positive bacteria, which colonize the skin and cause life-threatening infections in hospitalized patients. Results Candida auris ...
The issue is further proliferated by the increasing number of emerging fungal pathogens including MDR Candida auris, Fusarium spp. and Mucorales (Yousfi et al., 2019). Additionally, rare and emerging moulds including Lomentospora spp. and Scedosporium species have innate AMR and represent a ...
9and accounts for up to 10% of nosocomial blood stream infections (BSIs)10. Limited therapeutic options to treat invasive fungal infections, and increased emergence of antifungal drug resistance in related species such asCandida glabrataandCandida auris11,12,13pose a significant and growing health...
the NRRL 32931 genome encodes 70 ABC transporters—substantially more than other fungal species. Among these, the PDR/ABCG family, which contributes to resistance to xenobiotic compounds, has the highest number of representatives in the NRRL 32931 genome (27), followed by MDR/ABCB (20) and MRP...
Keywords Antifungal drug resistance · Public health · Aspergillus fumigatus · Trichophyton indotineae · Candida auris · One Health Introduction Fungi encapsulate a wide range of diversity, with an esti- mated 3.8 million species within this kingdom [1] and are currently ...
Candida spp. Azoles ERG11, ERG3,CDR1, CDR2, SNQ2, ABC1, MDR1, TPO3 Corynebacterium auris Azoles ERG11, ERG3, FKS Show moreView chapter Chapter INTRODUCTION Plant Pathology (Fifth Edition) Book2005, Plant Pathology (Fifth Edition) GEORGE N. AGRIOS Explore book The Etiological Phase The e...
(Figure 1). The conclusion that these compounds are acting as inhibitors of glucan synthesis is based on several lines of evidence: first, the spectrum of activity, being active againstAspergillusandCandidaspecies, but inactive againstCryptococcus; second, they induced the same alterations in the ...
9and accounts for up to 10% of nosocomial blood stream infections (BSIs)10. Limited therapeutic options to treat invasive fungal infections, and increased emergence of antifungal drug resistance in related species such asCandida glabrataandCandida auris11,12,13pose a significant and growing health...