Vitamin D3 is a prohormone produced in skin through ultraviolet irradiation of 7-dehydrocholesterol. It is biologically inert and must be metabolized to 25-hydroxyvitamin D3 in the liver and then to 1alpha,25-dihydroxyvitamin D3 in the kidney before function. The hormonal form of vitamin D3,...
Overview of general physiologic features and functions of vitamin D Vitamin D3 is a prohormone produced in skin through ultraviolet irradiation of 7-dehydrocholesterol. It is biologically inert and must be metabolized to 25... DeLuca Hector F - 《American Journal of Clinical Nutrition》 被引量: ...
The classical function of 1α,25(OH)2-D3 is regulation of calcium homeostasis [2]. However, vitamin D receptor (VDR) is expressed in tissues not involved in calcium metabolism. This indicates that 1α,25(OH)2-D3 is implicated in the regulation of many noncalcemic functions [3]. ...
享受闲适，而这种“慢生活”体现的是后工业时代的幸福导向型生活，随着这种观念的流行和它所催生的产业经济，未来人们会有更加丰富多彩的选择，过一种幸福导向型的生活。这体现了 ①一定的文化是一定经济的反映②文化在经济发展中起主导作用③文化与经济相互影响相互交融④经济具有的文化功能日见突出 It...
Results: Mean age was 63 ± 6.7 years and baseline vitamin D level was 7.8 ± 2.0 (range: 3.5–10.3) ng/ml. At 6 months, vitamin D level was 32.5 ± 3.4 (32.2–55) ng/ml. The Judgement of Line Orientation Test (P = 0.04), inaccurate word memorizing of the Verbal Memory ...
Vitamin D2orergocalciferolin plant foods andvitamin D3orcholecalciferolin animal foods and human skin are inactive forms of vitamin D. They are converted intocalcidiol (25OHD)in your liver and, finally, mainly in your kidneys, intocalcitriol (1-25OHD), which is the only active form of vita...
The sequence information of the human genome has facilitated the cloning in recent years of a number of extrahepatic cytochrome P450s like CYP2S1, CYP2R1, CYP2U1, CYP2W1 and CYP3A43. CYP2R1 has been shown to be active in the 25-hydroxylation of vitamin D2 and D3 but no xenobiotic ...
Distinctive downmodulation of plasmacytoid dendritic cell functions by vitamin D3 analogue calcipotrioldoi:10.1016/j.jdermsci.2016.06.003Background In relation to Th17 cell actions, interferon (IFN)-α production by plasmacytoid dendritic cells (pDCs) are involved in the pathogenesis of psoriasis. ...
Product Name:Vitamin D3 capsules;Shelf life:2 Years/ 24 Months;Sample:Support Sample;Color:White Color;Storage:Dry And Cool Place;Grade:Food Garde;Size:Accept Customized Size;Quantity per bottle:60 Capsules;MOQ:3000 Bottles;Package:Bottle Packing;Effecti
miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells. Oncotarget 2015; 6: 7675–7685. 39. Sun R, Liu Z, Wang L, Lv W, Liu J, Ding C et al. Overexpression of stathmin is resistant to paclitaxel treatment in ...