Functions of the outer membrane proteins of Neisseria gonorrhoeae - Blake - 1985 () Citation Context ... . BLAKE From the Laboratory of Bacteriology and Immunology, The Rockefeller University, Nero York 10021 The major outer membrane (OM)' proteins of Neisseria gonorrhoeae have been extensively ...
The nuclear compartment is delimited by a specialized expanded sheet of the endoplasmic reticulum (ER) known as the nuclear envelope (NE). Compared to the outer nuclear membrane and the contiguous peripheral ER, the inner nuclear membrane (INM) houses a unique set of transmembrane proteins that ...
Recently, palmitoylation of cysteine residues in membrane-proximal and cytosolically exposed domains has been shown to serve as a novel MAM sorting signal for ER membrane proteins. In a recent study, the palmitoylation status of the transmembrane domain of the thioredoxin family protein TMX (members...
Cellular stress induced by the abnormal accumulation of unfolded or misfolded proteins at the endoplasmic reticulum (ER) is emerging as a possible driver of human diseases, including cancer, diabetes, obesity and neurodegeneration. ER proteostasis surveillance is mediated by the unfolded protein response...
Proteins that function in the apicoplast must be targeted back to the organelle, which is accomplished by means of a bipartite leader sequence. Bioinformatic tools and their use to find the complement of apicoplast proteins are described. Apicoplast function The apicoplast is indispensable for paras...
Early region 3 genes of human adenoviruses contribute to the virus life cycle by altering the trafficking of cellular proteins involved in adaptive immunit... N.,L.,Cianciola,... - 《Journal of Virology》 被引量: 0发表: 2007年 Membrane-Based Functions in the Origin of Cellular Life If pe...
What is a Cell Membrane? Acell membraneis asemipermeableouter covering of cells. Cells in animals, plants, fungi, and prokaryotes have cell membranes. The cell membrane is made primarily of lipids and proteins and is a flexible structure, permitting cell growth. It divides the interior of a ...
Moreover, biological functions are expressed at various hierarchical levels (e.g. functional proteins such as ion channels, membrane, intracellular organelles, cells, tissues, whole organs, or integrated body functions, such as the systemic circulation). To take into account the hierarchical network ...
In the past decade, proteomic analyses have revealed that non-histone proteins are frequently acetylated and constitute a major portion of the acetylome in mammalian cells. Indeed, non-histone protein acetylation is involved in key cellular processes relevant to physiology and disease, such as gene ...
Phosphoinositides: lipid regulators of membrane proteins. J. Physiol. 588, 3179–3185 (2010). Article CAS PubMed PubMed Central Google Scholar Otsuguro, K. et al. Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate. J. Biol. Chem. 283, 10026–10036 (2008)...