What enzymes are involved in DNA replication? What is the role of telomerase in cells? Describe proteins. Identify the following nucleotide, and tell how it is used. What are the main structural features of an amino acid? What are all the types of interactions usually involved between a seque...
The cells of vertebrate organisms contain three distinct DNA polymerases which have been designed α, β and γ -polymerases (1). The information concerning the physical, chemical and catalytical properties of these enzymes has progressed considerably during the past few years so that the distinction...
The amount of DNA duplicated in each round of the replication cycle represents an unimaginable amount of information transfer. The DNA replication machinery thus includes and coordinates a massive complex of several proteins and enzymes working efficiently towards different subprocesses that combine for ...
The 1953 discovery of DNA’s structure by James Watson and Francis Crick created new opportunities for comprehending the functions of enzymes in genetic processes. Many enzymes involved in transcription, translation, and DNA replication were discovered in the decades that followed. ...
These proteins can be in the form of enzymes, which regulate the cell's biological and chemical processes. Enzymes are distinguished from other proteins by adding the suffix -ase to their names. DNA replication is heavily dependent on several enzymes to progress. An example of these enzymes is...
The orderly gene expression, DNA replication and damage repair play an important role in maintaining organism homeostasis, and aberrant of which usually results in a variety of diseases, such as cardiovascular diseases, liver diseases, nervous system disorders, diabetes, and neoplasms.7At the different...
et al. Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55(Gag). Proc. Natl Acad. Sci. USA 98, 7724–7729 (2001). CAS PubMed Google Scholar Martin-Serrano, J., Zang, T. & Bieniasz, P. D. HIV-1 and Ebola virus encode small ...
DNA ligase belongs to the nucleotide transferase superfamily, including RNA ligases andmRNAcapping enzymes. ATP-dependent ligases (based on Bacteriophage T7) NAD+ dependent ligases (based on E. coli LigA ligase) Types of DNA Ligase ATP dependent DNA ligases: ...
In view of the specificinteractions of nucleoside diphosphate kinase with T4 enzymes of DNA metabolism, howdoes T4 multiply after infection of this host? Finally, the ndk disruption strain has highlybiased nucleoside triphosphate pools, including elevations of the CTP and dCTP pools of7- and 23-...
As a prerequisite for understanding chromosome structure at the most detailed molecular level, the organization of chromatin structure including the histones is discussed. The past years of research have resulted in the discovery of numerous modifications on histones and the enzymes responsible for their...