In this article we are going to take a look at the structure and function of RNA along with all the different types of RNAs and in the process providing the actual definition of RNA.Share The chemical ribonucleic acid (RNA) can be found in the genomes of nearly all living thin...
Intergenic sRNAs have been studied intensively, and it was revealed that they have important regulatory functions under many different conditions. However, the numbers of cis-antisense RNAs and of cis-sense RNAs are much higher, and thus future research will shift to concentrate on their ...
Various biotypes of endogenous small RNAs (sRNAs) have been detected in human circulation, including microRNAs, transfer RNAs, ribosomal RNA, and yRNA fragments. These extracellular sRNAs (ex-sRNAs) are packaged and secreted by many different cell types. Ex-sRNAs exhibit differences in abundance in...
Protein domains of RNA helicases that are named after the Escherichia coli homologous recombination protein RecA. Argonaute A family of proteins that bind to various non-coding RNAs, including microRNAs, and mediate RNA silencing. Transport granules Ribonucleoprotein particles containing mRNAs, RNA-binding...
This cap is chemically similar to the 3′ end of the RNA molecule. This cap is uniquely found in small nuclear RNAs (snRNA) with a 5′ trimethylguanosine caps and in the long non-coding RNA (lncRNA) as 5′ monomethyl phosphate cap. ...
RNAs perform their function by forming specific structures, which can change across cellular conditions. Structure probing experiments combined with next generation sequencing technology have enabled transcriptome-wide analysis of RNA secondary structure in various cellular conditions. Differential analysis of st...
The major part of evolutionary "older" TEs accumulated mutations over time and fails to encode functional proteins. However, repeats have important functions also on the RNA level. Repetitive transcripts may serve as multifunctional RNAs by participating in the antisense regulation of gene activity and...
In this review, we give an overview of different fungal RNAi pathways with a focus on their mechanisms and functions. 展开 关键词: small noncoding RNA Schizosaccharomyces pombe Neurospora DOI: 10.1146/annurev-micro-092611-150138 被引量: 185 ...
Types and functions of RNA Of the many types of RNA, the three most well-known and most commonly studied aremessenger RNA(mRNA),transfer RNA(tRNA), andribosomal RNA(rRNA), which are present in all organisms. These and other types of RNAs primarily carry out biochemical reactions, similar to...
The most abundant of these molecules are the U1, U2, U5, and U4/U6 particles, which are involved in splicing pre-mRNA to give rise to mature mRNA. MicroRNAs Another topic of intense research interest is that of microRNAs (miRNAs), which are small regulatory RNAs that are approximately 22...