What are the functions of the sternocleidomastoid muscle? What are the functions of the large intestine? Describe the functions of the articular cartilage. Name and explain three functions of the skeletal system. Describe the function of tendons. ...
The importance of mTOR activity for articular cartilage destruction in OAis confirmed by significant changes in the work of mTOR regulatory network that involves multiple intracellular (growth factors, adenosine triphosphate, oxygen availability, and autophagy) and extracellular (glucose, amino acids, ...
Effect of polysulfated glycosaminoglycan on DNA content and proteoglycan metabolism in normal and osteoarthritic canine articular cartilage explants. To study the effect of polysulfated glycosaminoglycan (PSGAG) on proteoglycan metabolism and DNA content of control and osteoarthritic (OA) cartilage.An in....
Using microRNA expression profiling in healthy human articular cartilage cells (chondrocytes), we identified miR-1247 expression as highly correlated with that of the differentiated cell phenotype. Transcribed from the DLK1-DIO3 locus, the function of miR-1247 is completely unknown. In mice its ...
It is a group of mechanical abnormalities involving degradation of the joints and occurs when the protective cartilage (articular cartilage) on the ends of bones such as the knees, hips and fingers abrades over time. It mainly affects the whole joint structure, including the articular cartilage,...
In addition, ADAMTS proteins are known to cleave large aggregating proteoglycans, known as aggrecans, which comprise a large component of cartilage, especially articular cartilage. ADAMTS proteins that are known to cleave aggrecans are referred to as aggrecanases. The ADAMTS gene family includes five...
Integration of stem cell-derived exosomes with in situ hydrogel glue as a promising tissue patch for articular cartilage regeneration. Nanoscale. 2017;9(13):4430–8. Article CAS PubMed Google Scholar Feng H, Liu Q, Deng Z, Li H, Zhang H, Song J et al. Human umbilical cord mesenchymal...
TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage. J. Cell Biol. 153, 35–46 (2001). 54. Bonyadi, M. et al. Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice. Nat. Genet. 15, ...
Magnetic resonance (MR) images and relaxation and diffusion maps of articular cartilage were obtained to explain discrepancies in its MR appearance. Porcin... V Mlynárik,A Degrassi,R Toffanin,... - 《Magnetic Resonance Imaging》 被引量: 369发表: 1996年 The anisotropic structure of the upper ...
Jones S et al (2006) The orphan G-protein coupled receptor RDC1: evidence for a role in chondrocyte hypertrophy and articular cartilage matrix turnover. Osteoarthr Cartil 14(6):597–608 Article CAS PubMed Google Scholar Raggo C et al (2005) Novel cellular genes essential for transformation ...