Finding How an Essential Enzyme in the Malarial Parasite Plasmodium falciparum FunctionsIn the previous chapters, you have learned how to assign variables, do sums, perform comparisons, set conditions, and make choices. In the preceding chapter, I showed you how to store, process, and retrieve ...
An enzyme that is required to attach the molecular tag ubiquitin to proteins. Depending on the position and number of ubiquitin molecules that are attached, the ubiquitin tag can target proteins for degradation in the proteasomal complex, create a scaffold for assembly of signalling complexes, sort...
An enzyme-linked immunosorbent assay (ELISA) showed that the CES-1 concentration was higher in the OC mucus than in either the INM mucus or saliva (mean concentration: 5.73 μg/mL, 1.24 μg/mL, and 0.06 μg/mL, respectively, Fig. 3g). However, CES-1 did not fully account for ...
Multifunctional enzyme Intermediary metabolism 1. Introduction Living organisms are exposed to a large variety of fatty acids and their derivatives that can arise from either exogenous sources or endogenous synthesis. The fatty acids and their CoA esters play multiple roles in cellular processes by servi...
In addition, an outline of the variety of immunological processes depending on the activity of nicotinamide phosphoribosyltransferase (Nampt), the key enzyme of the salvage pathway of NAD+ synthesis, is presented. Taken together, an efficient supply of NAD+ seems to be a crucial need for a ...
an overview of the structure, function, and applications of RNA editing enzymes. We discuss the structural characteristics of three RNA editing enzyme families and their catalytic mechanisms in RNA editing. We also explain the biological role of RNA editing, particularly in innate immunity, cancer ...
Ferredoxin-NADP+ (oxido)reductase (EC 1.18.1.2, FNR) is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electr... AK Arakaki,EA Ceccarelli,N Carrillo - 《Faseb Journal Official Publication of the Federation of American Societies for Experimental Biology...
et al. Cleavage of polypeptide chain initiation factor eIF4GI during apoptosis in lymphoma cells: characterisation of an internal fragment generated by caspase-3-mediated cleavage. Cell Death Differ. 7, 628–636 (2000). Article PubMed CAS Google Scholar Nevins, T. A., Harder, Z. M., ...
PTENα (also known as PTEN-L) is the first identified isoform of PTEN, which contains an additional disordered 173-amino acid N terminus14,15. This region confers functions of PTENα that are distinct from those of PTEN14,15. The role of PTENα in tumors is complicated, which limits tumo...
The Clostridium paraputrificum chiB gene, encoding chitinase B (ChiB), consists of an open reading frame of 2,493 nucleotides and encodes 831 amino acids with a deduced molecular weight of 90,020. The deduced ChiB is a modular enzyme composed of a family 18 catalytic domain responsible for ...