this protein is not only an isopeptidase but also a potent inhibitor of interferon signaling. Therefore, USP18 functions as 'a' maestro of many biological pathways in various cell types. This review outlines multiple functions of USP18 in the regulation of various immunological processes, including...
CellStructureFunctionApplicationExtracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which is of great significance to tissue development. ECM in muscle fiber niche consists of three layers: the epimysium, the perimysium, and the endomysium (basal lamina). ...
Your thymus creates your T cells, which are a type of white blood cell. The proteins in your thymus help teach the T cells about which organs they're getting sent to. Your thymus prepares your cells to do a specific job for the remainder of their days. The main thymus gland function i...
RBCs are incapable of aerobic respiration, preventing them from consuming the oxygen they transport because they lose nearly all their inner cellular components during maturation. The inner cellular components lost include their mitochondria, which normally provide energy to a cell, and their nucleus, w...
Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which is of great significance to tissue development. ECM in muscle fiber niche consists of three layers: the epimysium, the perimysium, and the endomysium (basal lamina). These three layers of connective...
Odorants are detected by olfactory sensory neurons, which are covered by olfactory mucus. Despite the existence of studies on olfactory mucus, its constituents, functions, and interindividual variability remain poorly understood. Here, we describe a huma
Tests the hypothesis that activation of the cannabinoid CB1 receptor in cerebral vascular smooth muscle cells (VSMC) inhibits voltage-gated calcium channels and results in cerebral vasodilation. Suggestion that CB1 receptor and its endogenous ligand may play a role in the regulation of cerebral arteria...
The prevalence of coronary artery disease is increasing. As a common treatment method, coronary artery bypass transplantation surgery can improve heart problems while also causing corresponding complications. Venous graft restenosis is one of the most cr
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J. Cell Biol. 153, 1011–1022 (2001). CAS PubMed PubMed Central Google Scholar Jousse, C. et al. Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, ...
In recent years, increasingly more non-coding RNAs have been detected with the development of high-throughput sequencing technology, including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), small nucleolar RNAs (snoRNAs), a