The diverse functions of microRNAs in animal development and disease. MicroRNAs (miRNAs) control gene expression by translational inhibition and destabilization of mRNAs. While hundreds of miRNAs have been found, only a few h... WP Kloosterman,RHA Plasterk - 《Developmental Cell》 被引量: 4434发表...
Ambros V. The functions of animal microRNAs. Nature 2004; 431: 350 -5.V. Ambros, The functions of animal microRNAs, Nature 431 (2006) 350-355.The functions of animal microRNAs - Ambros - 2004 () Citation Context ... that almost a thousand miRNAs exists in humans, and while most are ...
She is a plant molecular biologist recognized for her work on sma... X Chen - 《Plant & Animal Genome》 被引量: 0发表: 2015年 MicroRNAs and their diverse functions in plants microRNAs (miRNAs) are an extensive class of newly identified small RNAs, which regulate gene expression at the ...
Another important part of the cell is the cytoplasm. It is a jelly-like substance that is present between the nucleus and the cell membrane. There are a number of other components or organelles of the cell that can be found in the cytoplasm. These aremitochondria, Golgi bodies, ribosomes, ...
In order to provide a cell with energy, these molecules have to pass across the cell membrane, which functions as a barrier — but not an impassable one. Like the exterior walls of a house, the plasma membrane is semi-permeable. In much the same way that doors and windows allow ...
and many of these are phylogenetically conserved. With miRNA roles identified in developmental timing, cell death, cell proliferation, haematopoiesis and patterning of the nervous system, evidence is mounting that animal miRNAs are more numerous, and their regulatory impact more pervasive, than was prev...
Conversely, females engineered to express fruM resemble normal females yet perform at least the initial stages of male courtship, albeit imperfectly [11, 12]. In contrast, the analogous mutations in dsx dramatically alter the animal’s appearance but have a comparatively milder impact on behavior, ...
The data and observations obtained during a limited study of megestrol acetate administered to 20 female patients over a 1-year period are presented in order to see the effects of such a steroid used either in a combination tablet or in a sequential manner on the function s of certain endocri...
T cells and endothelial cells. NK cells can thus limit or exacerbate immune responses. Although NK cells might appear to be redundant in several conditions of immune challenge in humans, NK cell manipulation seems to hold promise in efforts to improve hematopoietic and solid organ transplantation, ...
However, eight domains of Nsp3 exist in all known CoVs: the ubiquitin-like domain 1 (Ubl1), the Glu-rich acidic domain (also called “hypervariable region”), a macrodomain (also named “X domain”), the ubiquitin-like domain 2 (Ubl2), the papain-like protease 2 (PL2pro), the ...