1046 mitochondria in wilson disease (wd): functional and structural abnormalities in the toxic milk (tx-j) mousedoi:10.1016/S0270-9139(03)81084-4ROBERTS, ESABEAN, MYANG, SROBINSON, BElsevier Inc.Hepatology
B: MSC-mediated transfer of organelles (such as mitochondria), ions (such as calcium and magnesium), and small molecules (such as RNAs, proteins, and peptides) to damaged cells through tunneling nanotubes 研究表明, 外泌体和微泡是MSCs产生的最重要的胞外囊泡, 除大小和组成成分不同外, 它们的...
Immunoblots probed with an antiserum against the soluble IMS-localized chaperone Tim9 show that the mitochondrial OM is still intact in the isolated mitochondria that were used in the experiment (Fig. 2D, bottom panels). Thus, we conclude that, like yeast Tom22 and plant Tom9, ATOM14 is...
directly involved in different types of cognitive processes relying on brain oscillations, and myelin plasticity is currently considered to be part of the fundamental mechanisms for memory formation and maintenance. However, despite ample evidence showing the involvement of myelin in cognition and neurodeve...
& Lill, R. Iron-sulfur proteins in health and disease. Trends Endocrinol. Metab. 21, 302–314 (2010). 14. Stehling, O. & Lill, R. The role of mitochondria in cellular iron-sulfur protein biogenesis: mechanisms, connected processes, and diseases. Cold Spring Harb. Perspect. Biol. 5, ...
Cell health relies on mitochondrial activity since these organelles are the main producer of energy required for cellular functions. In particular, mitochondria are crucial for excitable cells, such as neurons, cardiac and skeletal muscle, that produce the energy brick adenosine-5′-triphosphate (ATP)...
Mitochondria enable oxidative phosphorylation and are intimately involved in apoptosis, both of which are key processes affecting cell survival under ischemic conditions [247]. As a result, perturbations of the mitochondrial genome or nuclear genes encoding mitochondrial proteins impact poststroke recovery....
Substrate Transformations dependent on Respiratory States of Mitochondria: Functional Status and Metabolic Changes in Rabbit Heart Mitochondria during Pyruvate ... SCHFER, G,BALDE, P,LAMPRECHT, W - 《Nature》 被引量: 14发表: 1967年 Functional status and radiographic joint damage are associated with ...
contributes to depletion of functional mitochondria in chronic MPP þ toxicity: dual roles for ERK1/2 JH Zhu1, AM Gusdon1, H Cimen2, B Van Houten3, E Koc4 and CT Chu*,1,5,6 The regulation of mitochondrial quality has emerged as a central issue in neurodegeneration, diabetes, and ...
Mitochondria are cellular organelles critical for numerous cellular processes and harboring their own circular mitochondrial DNA (mtDNA). Most mtDNA associated disorders (either deletions, mutations, or depletion) lead to multisystemic disease, often sev