The generation of functional pancreatic beta cells from human pluripotent stem cells (hPSCs) is a main goal of stem cell research, aiming to provide a renewable and consistent source of cells for the treatment of diabetes. Stem-cell-derived beta cells could solve the limitations of using cadaveri...
School of Biosciences and Veterinary Medicine, Plant Diversity and Ecosystems Management Unit, University of Camerino, Camerino, Italy Giandiego Campetella DiSTA, University of Insubria, Varese, Italy Bruno E. L. Cerabolini Institute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, AK, ...
University of Lausanne, Lausanne, Switzerland 3 Ludwig Lausanne Branch, Lausanne, Switzerland 4 Institute of Cellular and System Medicine, National Health Research Institute, Miaoli, Taiwan, ROC invading pathogens as well as the maintenance of alveolar microenvironment by clearing pollutant and surf...
The Andean highlands of Ecuador, characterized by cooler temperatures and volcanic soils, offer optimal conditions for a diverse range of plant life, several of which are utilized as traditional food and medicine [5,6]. The Caricaceae family comprises six genera and forty-two species, of which ...
2Nuffield Department of Medicine Research Building, Alzheimer's Research UK Oxford Drug Discovery Institute, University of Oxford, Oxford OX3 7FZ, UK. 3Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK. 4UK Dementia Research Institute, Cardiff University, Cardiff...
After a dorsal root crush injury, centrally-projecting sensory axons fail to regenerate across the dorsal root entry zone (DREZ) to extend into the spinal cord. We find that chemogenetic activation of adult dorsal root ganglion (DRG) neurons improves axo
Poly(ADP-Ribose) Polymerase 1–Sirtuin 1 Functional Interplay Regulates LPS-Mediated High Mobility Group Box 1 Secretion Thomas D Walko III,1 Valentina Di Caro,1 Jon Piganelli,2 Timothy R Billiar,3 Robert SB Clark,4 and Rajesh K Aneja4 1Department of Critical Care Medicine, 2Department of...
Department of Pathology, School of Medicine, University of California at San Diego, La Jolla, CA, 92037, USA Gen-Sheng Feng Laboratory of Neurobiology, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 2770...
Santa Fe Institute, Santa Fe, NM, 87501, USA Danielle S. Bassett Lifespan Brain Institute, Penn Medicine and Children’s Hospital of Philadelphia, Philadelphia, PA, 19104, USA Monica E. Calkins, Raquel E. Gur, Ruben C. Gur, Tyler M. Moore, David R. Roalf, Daniel H. Wolf & Theodore...
8Department of Anesthesiology, Intensive Care and Pain Medicine, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, Finland. 9Center for Pain Research and Innovation, University of North Carolina, Chapel Hill, NC, 27599, USA. *These authors contributed equally to this work. ...