Local intravitreal or intra-arterial chemotherapy has improved therapeutic success for the pediatric cancer retinoblastoma (RB), but toxicity remains a major caveat. RB initiates primarily with RB1 loss or, rarely, MYCN amplification, but the critical do
Foods for special dietary requirements include commercially available foods such as infant formula [10], gluten-free products and lactose-free dairy products to accommodate food intolerances and allergies [7]. The last group of medical foods differ from foods for special dietary requirements by being...
Downloadkeyboard_arrow_down Browse Figures Versions Notes Abstract PNPT1(PNPase—polynucleotide phosphorylase) is involved in multiple RNA processing functions in the mitochondria. Bi-allelic pathogenicPNPT1variants cause heterogeneous clinical phenotypes affecting multiple organs without any established genotype–...