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Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling. Nature 548, 602-606 (2017).Yang K et al (2017) Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling. Nature 548:602-606...
thus, often referred to as passenger mutations, while a smaller set of driver mutations will actually confer growth advantages to tumors (Greenman et al.2007; Sjoblom et al.2006). Driver mutations increase the fitness of cells that they reside in and are assumed to be under positive...