DISCLOSURE Drs Heath D Schmidt and Ronald S Duman report no biomedical financial interests or potential conflicts of interest. Richard C Shelton, MD, has served as a consultant for Eli Lilly & Company, Evotec AG, Forest Pharmaceuticals, Janssen Pharmaceutica, Medtronic Inc., Otsuka Pharma- ...
Author Contributions: Drs Wright and Stoddard had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Willis, Tennstedt, Marsiske, Ball, Morris, Rebok, Unverzagt, Wright. Acquisitio...
We also acknowledge the valuable material and intellectual contributions of Drs. Edward Ginns and Marzena Galdzicka to this study. Author information Author notes Authors and Affiliations Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, MA, 02142, USA Ruqi Tang, Hyun Ji Noh, ...
The authors would like to thank Drs. A. Kimura (TMDU), M. Watanabe (TMDU) and S. Nishikawa (Kyoto University) for helpful discussions, and the Research Core Center (RCC at TMDU) for the ultrathin section preparations used in the electron microscopy studies. The authors would like to thank...
From the front desk staff, to the Drs, to the tea in the waiting room, this was a quality experience. 23:39 04 Jul 24 Love this team of women! Great doctors and great personalities and they are exceptional with improving your health! 17:37 20 Jun 24 I was honestly skeptical. I ...
(ce, cassette exon; 5ss, alternative 5′ splice site; me, mutually exclusive exon; complex, multiexonic rearrangement; 3ss, alternative 3′ splice site; ir, intron retention) and (b) involvement in apoptosis and/or cell proliferation regulation, as well as information on the category of ...
All fish were allowed to acclimate to the system for one month while receiving the control diet. Photoperiod followed natural cycles (Aug.–Nov.) and seawater pumped from an adjacent bay (Taunton Bay, Franklin, ME, USA) followed ambient temperatures (Additional file1; Figure S1). Water quality...
Both in vitro and in vivo studies suggest that deletion of these DRs reduces CHIKV fitness in mosquito vectors but can increase fitness in mammalian models. Presumably, the CHIKV 3′ UTR enhances viral replication in mosquitoes by interacting with mosquito cell-specific factors. However, it is ...
Germline pathogenic variants in DNMT3A were recently described in patients with overgrowth, obesity, behavioral, and learning difficulties (DNMT3A Overgrowth Syndrome/DOS). Somatic mutations in the DNMT3A gene are also the most common cause of clonal hem
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