We explored a 12-dimensional parameter space of a 2-compartment model of the AB (anterior burster) neuron, which is one of the two cells that form the pacemaker kernel in the pyloric network in the lobster stomatogastric ganglion (STG). The computational exploration started with a hand-tuned...
BMC Neuroscience 2010 11(Suppl 1) - Rough () Citation Context ...fication tasks is the concept of a reduct鈥攖he smallest possible subset of attributes (i.e., maximal conductances in our model) that preserves the classification accuracy of the full set of attributes =-=[4]-=-. There ...
- 《Neuron》 被引量: 2218发表: 2011年 The American College of Rheumatology 1991 revised criteria for the classification of global functional status in rheumatoid arthritis. Conclusion. Although there are limitations inherent in the use of global ordinal scales, the American College of Rheumatology ...
localizationist voxel-based approach. We used independent component analysis (ICA) to extract the task-specific activity of functional connectivity networks (FCNs) for our network-based analysis. As brain activity differs between tasks and between populations of individuals, using this data-driven proced...
,... - 《Neuron》 被引量: 69发表: 2015年 In silico binary classification QSAR models based on 4D-fingerprints and MOE descriptors for prediction of hERG blockage. This binary model achieves 91% accuracy over a large range of molecular diversity spanning the training set. Two external test ...
Transcranial focused ultrasound (tFUS) is a promising neuromodulation technique, but its mechanisms remain unclear. We hypothesize that if tFUS parameters exhibit distinct modulation effects in different neuron populations, then the mechanism can be unde
Human functional-anatomic correlates of object repetition were explored in a cohort of 20 subjects using fMRI. Subjects performed an object classification ... RL Buckner,J Goodman,M Burock,... - 《Neuron》 被引量: 1198发表: 1998年 Distribution of alpha 2 agonist binding sites in the rat and...
(RA), these factors precisely pattern the neural tube into spinal cord progenitor domains pd1~6, p0, p1, p2, motor neuron progenitor (pMN), and p3 along the dorso-ventral axis (Figure2a). This patterning is mediated by distinct expression of cross-repressive transcription factors—specifically,...
(Fig.3a). Then, the topological architecture of intra-module and inter-module connection networks was analyzed. First, by reorganizing the position of vertices in each group network’s adjacency matrix based on this classification, a substantial structure that was disappearing with the progression of...
Neurons in sensory systems often pool inputs over arrays of presynaptic cells, giving rise to functional subunits inside a neuron’s receptive field. The organization of these subunits provides a signature of the neuron’s presynaptic functional connecti