This chapter presents the tests and functions of thyroid. Nearly all the circulating, organically bound iodine is normally incorporated in thyroxine (T4). More than 99% of this T4 is bound to a specific thyroxine-binding globulin (TBG); this bound T4 is physiologically inactive. The protein-...
Thyroid gland, endocrine gland that is located in the anterior part of the lower neck, below the larynx (voice box). The thyroid secretes hormones vital to metabolism and growth. Any enlargement of the thyroid, regardless of cause, is called a goitre. Th
Define hyperfunction. hyperfunction synonyms, hyperfunction pronunciation, hyperfunction translation, English dictionary definition of hyperfunction. n 1. med excessive activity or functioning 2. maths a pair of holomorphic functions distinguished by a b
The authors studied function by dosage of total T3 and , corresponding free portions, globulin (), (TSH) and reverse T3 (rT3) in 68 clinically euthyroid patients, treated with , divided in two groups including 25 subjects treated for less than one month and 43 subjects in therapy for more...
Thyro- globulin structure-function: isolation and charac- terization of thyroxine containing polypeptide from bovine thyroglobulin. 9425-9430. J. Biol. Chem. 256,Chernoff, SB, Rawitch, AB (1981) Thyroglobulin structure-function: Isolation and characterization of a thyroxine-containing polypeptide from ...
of the patients given TRH responded to ECT. One patient's reaction is of special significance because of her response to ECT, diminished thyroid- stimulating hormone response to TRH, increased growth hormone and prolactin response to stress, and antidepressant effect of TRH. These findings raise ...
Thyroid hormones (TH) cross the plasma membrane with the help of transporter proteins. As charged amino acid derivatives, TH cannot simply diffuse across a lipid bilayer membrane, despite their notorious hydrophobicity. The identification of monocarboxylate transporter 8 (MCT8, SLC16A2) as a specifi...
and triiodothyronine (T 3) uptake measurements were performed as the initial tests of thyroid function on 490 patients admitted to a geriatric department. Up to 20 % of the euthyroid patients had reduced thyroxine-binding-globulin (T.B.G.) levels. Interpretation of these tests is difficult ...
thyroid function test, any laboratory procedure that assesses the production of the two active thyroid hormones, thyroxine (T4) and triiodothyronine (T3), by the thyroid gland and the production of thyrotropin (thyroid-stimulating hormone, TSH), the hormone that regulates thyroid secretion, by the ...
Serum thyroxin values (T4) were found to be low in 6 of 1350 admissions when the tests were ordered on clinical grounds. Hypothyroidism was confirmed in 3 infants, but the remaining 3 had transient depressions of 3, due to binding globulin (TBG) deficiency. Consequently, a longitudinal study...