DNAJB6, were identified in patients with LGMDD1, a dominant autosomal disorder characterized by myofibrillar degeneration and accumulations of aggregated protein within myocytes. The molecular mechanisms through
unc-89 is also expressed in the single sarcomere muscle cells of the pharynx. UNC-89 is normally localized to the middle of the A-bands of pharyngeal sarcomeres8,10. All previously characterized unc-89 mutants, except for unc-89(tm752), have abnormally organized filaments as observed by pol...
The nature and diversity of the perciforms make a general definition of the group difficult; the most common characters are found in the large families of sea basses, mackerels, perches, sunfishes, and others. Perciform fishes usually have spines present on their dorsal, anal, and pelvic ...
The esophagus is the tube that connects the pharynx to the crop of an earthworm. The crop is where the food is stored and softened. The gizzard serves as the stomach of an earthworm. The ventral nerve cord is a group of nerves in the abdomen. The seminal receptacle is a pocket containin...
Hco-gal-m was expressed in L4 as well as adult worms and predominantly localized at the internal surface of the worm guts. rHco-gal-m could bind to both monocytes and T cells. The engagement of rHco-gal-m decreased the production of IL-6, IL-10 and TNF-α in T cells, however, ...
The phylum Mollusca is one of the largest and more diversified among metazoan phyla, comprising many thousand species living in ocean, freshwater and terre
Average intensity of head region excluding mouth, pharynx, and intestine quantified. (h) Lifespan analysis (% of worms surviving since days hatching) of N2 and har-1 KO worms at 16 °C (Log-rank Mantel–Cox test, ##Po0.0001, n ¼ 170 worms/strain). All quantitative graphs with error...
Therefore, we conclude that CBP3 affects cell maintenance and differentiation for neural lineages and potentially other cell types, in particular those of the pharynx. Notably, the changes elicited by CBP3(RNAi) are distinct from those caused by loss CBP2. 4. Conclusion In our search for novel...
Ethosuximide is a medication used to treat seizure disorders in humans, and we previously demonstrated that ethosuximide can delay age-related changes and extend the lifespan of the nematode Caenorhabditis elegans. The mechanism of action of ethosuximide
The three interface modalities were assessed in 11 OSAS patients at 6, 8, 10 cmH(2)O CPAP using a phrenic nerve magnetic stimulation (PNMS) protocol. PNMS-twitches' related flow, pharyngeal pressures (nasopharynx, velopharynx, oropharynx) and UA resistances were determined. Regardless of CPAP ...