The detailed positions of nucleosomes along genomes have critical roles in transcriptional regulation. Consequently, it is important to understand the principles that govern the organization of nucleosomes in vivo, and the functional consequences of this organization. I will present our progress in ...
DnaJ proteins function as cofactors by regulating the activity of a member of the 70-kD heat shock protein family. Genetic analyses demonstrated that amino... KS Campbell,KP Mullane,IA Aksoy,... - 《Genes Dev》 被引量: 458发表: 1997年 HSP90 affects the expression of genetic variation and...
The most widely recognised DNA structure is that of the classical DNA double helix [1], which defines a structural basis for the genetic code via defined base-pairing. Yet, it is evident that DNA is structurally dynamic and capable of adopting alternative secondary structures. One such class ...
The code used to perform Poisson surface reconstruction from segmentation output is located athttps://github.com/broadinstitute/ml4hand is available under an open-source BSD license. The code used to perform permutation testing to assess enrichment of disease-related genes near GWAS loci is located...
to break it down it combines first char of each and then second char of each. In each case it checks if the order is wrong (i.e. "RR", "Rr", and "rr" are all OK, only "rR" is backwards) then reverse it: =CONCAT(
The genetic complementation (dominance) is observed to contribute to heterosis in Arabidopsis, maize and rice11,12,13. Large-scale genomic analysis based on commercial rice hybrids and associated populations, provides the support for partial dominance of heterozygous loci for yield-related traits, and...
The genetic code is redundant, meaning that most amino acids can be encoded by more than one codon. Highly expressed genes tend to use optimal codons to increase the accuracy and speed of translation. Thus, codon usage biases provide a signature of the relative expression levels of genes, whic...
This technique allowed for a larger deletion of genetic code that permanently destroyed the targeted gene. Tsang found that using two guide RNAs instead of one increased the chance of disrupting the bad gene from 30 percent to 90 percent. ...
of the algal genes were transferred to the nuclear genome, plastids have retained a complete protein synthesizing machinery and enough information to code for about 100 of their approximately 2,500 proteins; all other plastid proteins are coded for by the nuclear genome and imported from the ...
Code availability The intron retention was evaluated using IRFinder62(https://github.com/williamritchie/IRFinder). All of the software and packages used in this article have been listed in the Reporting Summary and are publicly available.