RECENTLY ansystem for DNA replication has been described. This system could be divided into two fractions (A and B) both of which are necessary for proper DNA replication. Fraction A, the "soluble" fraction, contains those proteins which do not tightly bind to membranes or native DNA. ...
DNA polymerase epsilon T cell B cell lymphopoiesis non-replicative function Introduction Cell differentiation in the developing organism is orchestrated by a complex interplay of extrinsic and cell-intrinsic factors. Lymphocytes of the T and B cell lineages fall into a special category, as they are ...
DNA polymerase catalyzes the process of DNA replication and repair during cellular respiration. Learn about DNA polymerase function, structure, and...
Describe the function of DNA polymerase I. What function does DNA ligase perform in the cell? Identify the function of the protein: DNA ligase. Describe the structure and function of DNA. What is the function of DNA ligase in DNA replication? Describe the function of DNA polymerase I in lea...
Telomerase is a RNA-dependent DNA polymerase that synthesizes telomeric repeats at the end of eukaryotic chromosomes1. This enzyme complex consists of a catalytic protein with a telomere-specific reverse transcriptase activity (TERT), an internal RNA template (TR) and a number of associated proteins...
Background: During bacteriophage T4 DNA replication, the 44/62 and 45 accessory proteins combine with the DNA polymerase to form a processive holoenzyme complex. Formation of this complex is dependent upon ATP hydrolysis by the 44/62 protein. It is uncertain, however, whether the 44/62 protein...
Poly(ADP-ribose) polymerase (PARP) participates in the intricate network of systems developed by the eukaryotic cell to cope with the numerous environmental and endogenous genetoxic agents. Cloning of the PARP gene has allowed the development of genetic and molecular approaches to elucidate the struct...
Table 4.1 lists all 20 proteinogenic amino acids present in peptides which interact with MHC molecules. There are different criteria for grouping amino acids, such as the size of side chains, polarity, charge or hydrophobicity. Regarding the specific cha
We have previously shown that Sindbis virus RNA polymerase requires an N-terminal aromatic amino acid or histidine for wild-type or pseudo-wild-type function; mutant viruses with a nonaromatic amino acid at the N terminus of the polymerase, but which are otherwise wild type, are unable to pro...
Chloroplasts are key players in photosynthesis and immunity against microbial pathogens. However, the precise and timely regulatory mechanisms governing the control of photosynthesis-associated nuclear genes (PhANGs) expression in plant immunity remain l