iAnnteortnhaelrizkaetyiofneawtuarseroefceRnNtlAyiviinsuCa.leilzeegdanisnisvitvhoa,t iint cislusdyisntegmthice, deposition of dsRNA into oocytes and embryos [26]. Another key feature of RNAi in C. elegans is that Non-coding RNA 2019, 5, 8 4 of 24 that is, dsRNA spreads throughout the...
Cardiac-restricted RNAi-mediated knockdown of TER94, the Drosophila VCP homolog, severely perturbed myofibrillar organization and heart function in adult flies. Furthermore, expression of MSP disease-causing alleles engendered cardiomyopathy in adults and structural defects in embryonic hearts. Drosophila ...