Structurally speaking,ribonucleic acid (RNA), is quite similar to DNA. However, whereas DNA molecules are typically long and double stranded, RNA molecules are much shorter and are typically single stranded. RNA molecules perform a variety of roles in the cell but are mainly involved in the proc...
Heredity is the study of how genes are inherited in offspring. Heredity involves the study of the genetic molecules DNA and RNA. Understanding how DNA and RNA work will allow for better understanding of how genes will be inherited in offspring. ...
Growing evidence is implicating non‑B-form DNA structures in processes related to DNA stability and function, including replication and transcription. In particular, genomic studies are suggesting that sequences that could form G-quadruplex structures
RNA-binding proteins (RBPs) play an essential role in regulating the function of RNAs in a cellular context, but our ability to control RBP activity in time and space is limited. Here, we describe the engineering of LicV, a photoswitchable RBP that binds to a specific RNA sequence in resp...
一般这些碱基在核酸 中的含量稀少,在各种类型核酸中的分布也不均一。DNA中的修饰碱基主要见于噬菌体DNA,如5-甲基胞嘧啶(m5C),5-羟甲基胞嘧啶 hm5C;RNA中以tRNA含修饰碱基最多,如1-甲基腺嘌呤(m1A),2,2一二甲基鸟嘌呤(m22G)和5,6-二氢尿嘧啶(DHU)等。
Fast hash function for DNA/RNA sequences. Contribute to bcgsc/ntHash development by creating an account on GitHub.
摘要: The versatility of RNA structure and function. Jacques Monod Conference: New insights into the mechanism of mRNA translation: the significance of RNA structure, Aussois, France, 22-26 March 1999. - ResearchGateDOI: 10.1016/S0168-9525(99)01779-5 ...
我们在标题中搜索了关键词“complex”,然后删除了所有分辨率低于2.5Å,与RNA或DNA形成复合物,是理论模型,包含与蛋白质共价结合的配体,或是肽抑制剂的条目。这产生了1269个条目。我们仅保留了那些具有相同PDB条目四个字母识别代码的第二个和第三个字母的第一个条目,因为它们包含相似的蛋白质结构。这产生了697个条目...
比如说,STABILIZED 1和RDM16这两个剪切因子的突变会降低POL V依赖性支架RNA的积累。据推测,一些能够结合mRNA前体的剪切因子可能会跟由POL IV和POL V产生的非编码转录本结合,并影响它们的加工或是稳定性,进而影响siRNA或支架RNA的丰度。 Maintenance of DNA methylation...
Binding of DNA and of RNA are no longer considered functionally distinct, partly owing to the discovery that DNA- and RNA-binding proteins (DRBPs) can bind long non-coding RNAs and DNA. The unique functional characteristics of DRBPs stem from their speci