Growing evidence is implicating non‑B-form DNA structures in processes related to DNA stability and function, including replication and transcription. In particular, genomic studies are suggesting that sequences that could form G-quadruplex structures
select article Isoform balance of the long noncoding RNA NEAT1 is regulated by the RNA-binding protein QKI, governs the glioma transcriptome, and impacts cell migration Research articleOpen access Isoform balance of the long noncoding RNA NEAT1 is regulated by the RNA-binding protein QKI, ...
Binding of DNA and of RNA are no longer considered functionally distinct, partly owing to the discovery that DNA- and RNA-binding proteins (DRBPs) can bind long non-coding RNAs and DNA. The unique functional characteristics of DRBPs stem from their speci
Understanding the structure and function of small RNAs, such as siRNAs and miRNAs, that trigger RNAi has shed light on the RNAi machinery. In particular, it has highlighted the assembly and function of the RNA-induced silencing complex (RISC), and has provided guidelines to efficiently silence ...
Fast hash function for DNA/RNA sequences. Contribute to bcgsc/ntHash development by creating an account on GitHub.
我们在标题中搜索了关键词“complex”,然后删除了所有分辨率低于2.5Å,与RNA或DNA形成复合物,是理论模型,包含与蛋白质共价结合的配体,或是肽抑制剂的条目。这产生了1269个条目。我们仅保留了那些具有相同PDB条目四个字母识别代码的第二个和第三个字母的第一个条目,因为它们包含相似的蛋白质结构。这产生了697个条目...
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and regulates transcription of genes involved in cell proliferation/differentiation (25, 26, 27, 28), the +KTS isoform binds RNA rather than DNA and has been shown to be associated and localized with splicing factors (29, 30, 31, 32), suggesting a role for this isoform in RNA processing....
and Masamichi Nishiguchi 14. Using Nuclear Run-On Transcription Assays in RNAi Studies Basel Khraiwesh 15. Proteomic Analysis of RNA-Interference Induced Knockdown Plant Sang Yeol Lee and Kyun Oh Lee 16. Comparative Analysis of Phosphoprotein Expression using 2D-DIGE Tomoya Asano and Takumi Nishiuchi...
(RNA-Seq) of total lungs from male and female CC-LR and LR/Stat3Δ/Δmice at the age of 14 weeks (n = 3 each group;n = 12 total). Using the Ion Torrent Proton, we sequenced an average of 42 million reads per specimen (Supplementary Table1). To determine sex-dependent ...