function of the heart including histology and apoptosis of cardiomyocytes were detected using biochemistry,histology,transmission electron microscopy,and quantitative pathology.Results The values of LDH,AST and CK of the hypoxic rats were higher than that of the control group and the increase became ...
We conclude that energy uncoupling between VO2 and PVA in hypothermically preserved heart is attributable to disturbed mitochondrial oxidative phosphorylation and that 8 h is a critical point for efficient conversion of energy from VO2 into PVA in rat heart. 展开 ...
These observations indicate that NB rat heart contains fully functional RyRs and that the smaller contribution of RyR-mediated Ca2+ release to the intracellular Ca2+ transient in NB is not due to different single RyR channel properties or to the absence of functional intracellular Ca2+ stores....
Cardiomyocytes derived from human embryonic stem (hES) cells potentially offer large numbers of cells to facilitate repair of the infarcted heart. However, this approach has been limited by inefficient differentiation of hES cells into cardiomyocytes, in
(LUAD) is the most common histological subtype of NSCLC accounting for over 50% of diagnosed lung cancer cases2,3. The Kirsten rat sarcoma viral oncogene (K-ras) is the most commonly mutated oncogene in LUADs (~25–30%) particularly in those that developed in lifetime smokers4,5. ...
congestive heart failure, the left ventriicular systolic function w as mea ssured with echocardiography before and after treatment, effects on the concentra tion of cyclic adenosine monophosphate and leakage of intracellular lactat e dehydrogenase in cultured neonatal rat cardiomyocytes were investigated. ...
Other side effects include acne, headache, liver tumors, kidney disease, high blood pressure, heart disease, and muscle spasms. Women who take anabolic steroids can also become infertile and suffer all of the aforementioned side effects plus beard growth, voice deepening, breast atrophy, and an ...
Trace versus delayed conditioning of heart rate in rats as a function of us intensity Classical conditioning of heart rate (HR) and skeletal-motor activity in restrained rats was examined using a single, brief (.5-msec) pulse of shock to the rat's tail as both the CS and US. Electric ...
We sought to characterize the inhibition status of the mitochondrial permeability transition early after the post-conditioning maneuver and before long reperfusion was established. We observed that post-conditioning maneuvers applied to isolated rat hearts, after a prolonged ischemia and before reperfusion,...
et al. Structural and functional properties of adult rat heart myocytes lysed with digitonin. J. Biol. Chem. 260, 14325–14334 (1985). CAS PubMed Google Scholar Dzeja, P.P., Bortolon, R., Perez-Terzic, C., Holmuhamedov, E.L. & Terzic, A. Energetic communication between ...