The expression of MMPs is regulated by cytokines and signal transduction pathways, including those activated by phorbol myristate acetate (PMA). We found that resveratrol, a phytoalexin present in grapes, significantly inhibits the PMA-induced increase in MMP-9 expression and activity. These effects...
Cholinergic innervation and function in the prostate glandVenturaS.PennefatherJ. N.MitchelsonF.PHARMACOLOGY AND THERAPEUTICSVentura S, Pennefather J, Mitchelson F (2002). Cholinergic innervation and function in the prostate gland. Pharmacol Ther 94:93-112....
The concentration in the ejaculate of the majority of the parameters investigated did not change with age, although the total contribution to the ejaculate from the prostate and seminal vesicles was reduced significantly in the older men. The concentration of three constituents was significantly altered...
Prostate cancer is the most frequently diagnosed non-skin cancer and the third leading cause of cancer mortality among men in the US. Androgens are functionally required for the normal growth of the prostate gland and play a critical role in prostate tumor development and progression. Epithelial-...
1. Supports a Healthy Prostate Size As men get older, hormonal imbalances can cause the prostate gland to enlarge, resulting in uncomfortable urinary symptoms. TitanFlow features ingredients that help regulate dihydrotestosterone (DHT) levels, a hormone associated with prostate enlargement. By managing ...
Prostate Gland Bulbourethral Glands The Male Reproductive System External Male Reproductive Structures External organs of the male reproductive system are present outside the body and are mainly utilized in the act of sexual intercourse. They consist of 3 main organs: Penis Scrotum Testes The External...
Infertile men have few treatment options. Here, we demonstrate that the transmembrane receptor activator of NF-kB ligand (RANKL) signaling system is active in mouse and human testis. RANKL is highly expressed in Sertoli cells and signals through RANK, expressed in most germ cells, whereas the RA...
The urethra, which carries the ejaculate to be expelled during orgasm, runs through the center of the prostate gland. Your prostate also converts some of your testosterone into another hormone, called dihydrotestosterone (DHT), which plays a part in sexual development throughout your life. When ...
Autophagy-lysosome system plays a variety of roles in human cancers. In addition to being implicated in metabolism, it is also involved in tumor immunity, remodeling the tumor microenvironment, vascular proliferation, and promoting tumor progression and
Prostate cancer, next to lung cancer, has the highest incidence of any form of cancer affecting men in this country. About 100,000 new cases are diagnosed each year, accounting for more than 17% of all cancer in males. It has been proposed that steroid hormones, chemical carcinogens, viral...