The function of natural killer cells: education, reminders and some good memories[J] . Werner Held,Mika Kijima,Georgi Angelov,Stéphanie Bessoles.Current Opinion in Immunology . 2010 (2)Held W, Kijima M, Angelov G, Bessoles S: The function of natural killer cells: education, reminders and ...
Furthermore, NK cells from the NPC1 mouse demonstrated defective cytotoxicity, which was the result of reduced lysosome calcium content/release of NPC1 NK cells. These findings have important clinical implications for the treatment and management of NPC1 patients and also identify NK cells as a ...
Conclusion: Lidocaine showed an important stimulatory activity on NK cells. Our findings suggest that lidocaine might be used perioperatively to minimize the impact of surgery on NK cells. 展开 关键词: Lidocaine cancer cells cytotoxicity natural killer cells ...
Summary: T cells and natural killer (NK) cells are presumed to share a common intrathymic precursor. The development of conventional a|3 T lymphocytes begi... James,R.,Carlyle,... - 《Immunological Reviews》 被引量: 72发表: 1998年 T-cell and natural killer cell development in thymectomi...
Immunological memory is a hallmark of the adaptive immune system. Although natural killer (NK) cells are innate immune cells important for the immediate host defence, they can differentiate into memory NK cells. The molecular mechanisms controlling this
Whalen.Effect of a series of triorganotins on the immune function of human natural killer cells[J]. Environmental Toxicology and Pharmacology .2006(1)Gomez F.D., Apodaca P., Holloway L.N., Pannell K.H., Whalen M.M. Effect of a series of triorga- notins on the immune function of ...
Inhibitory receptors antagonize natural killer cell cytotoxicity. Ge and colleagues show that the scaffold protein β-arrestin 2 recruits the phosphatases SHP-1 and SHP-2 to the inhibitory receptor KIR2DL1 to enhance 'downstream' inhibitory signaling. Th
Natural killer (NK) cells kill virally infected/transformed cells via degranulation of lysosome-related organelles. Their trafficking from lymphoid tissues into the circulation is dependent on sphingosine-1-phosphate (S1P) gradients, sensed by S1P receptor 5 (S1P5). We hypothesized that NK-cell ...
Natural killer cell biology: An update and future directions Natural killer (NK) cells constitute a minor subset of normal lymphocytes that initiate innate immune responses toward tumor and virus-infected cells. They... KS Campbell,J Hasegawa - 《Journal of Allergy & Clinical Immunology》 被引量...
NK cells are natural cytotoxic killer cells inhuman bloodand are a type of lymphocyte, a subgroup of white blood cells or leukocytes. They are able to identify and kill abnormal cells such as tumor cells or virally infected cells (apoptosis). Up until now, NK cells have been regarded as ...