MonocytesCytokinesOrofacial infectionsFew data are available on the significance of the integrity of the innate immune system among patients with orofacial infections. This was assessed in the present study. Peripheral blood mononuclear cells (PBMCs) were isolated from 23 patients with orofacial ...
Blood samples incubated with LPS for 2 hours but only exposed to liposomes for 30 min had monocytes with a thromboplastin activity of 30x10/10-3cells as compared to an activity of 152x10 /10-3cells in the monocytes of blood incubated with LPS and liposomes for 2 hours. Although the ...
The cellular origin of pro-inflammatory cytokine activity remains unclear, although monocytes are considered the main contributors in peripheral blood [128]. TLR4-mediated lipopolysaccharide ligation has been shown to significantly increase IL-6 and TNF-α production in peripheral blood monocytes following...
Dysfunction of peripheral blood dendritic cells from patients with chronic hepatitis B virus infection AIM To identify the property of dendritic cells(DCs)of peripheral blood monocytes(PBMC)in patients with chronic HBV infection. METHODS Twenty patients with... Fu-Sheng Wang1,LH Xing,MX Liu,... ...
In order to study the molecular mechanisms underpinning monocyte impairment, we adopted the approach of isolating CD14 monocytes from whole blood of healthy volunteers and used a model of endotoxin tolerance similar to that of other groups15,16. Our experience with this model regarding the purity an...
Our study demonstrates a notable enrichment of S100A9+CD14+ monocytes in the peripheral blood of patients exhibiting suboptimal responses to anti-PD-1 therapy. Moreover, we identified the Mono_S100A9 signature as a predictive biomarker, indicative of reduced efficacy in immunotherapy and decreased sur...
Lipoteichoic acidCytokinesMonocytesDespite similar clinical relevance of Gram-positive and Gram-negative infections, immune activation by Gram-positive bacteria is... C Draing,S Sigel,S Deininger,... - 《Immunobiology》 被引量: 167发表: 2008年 Cytokine induction by purified lipoteichoic acids from var...
PMN cells (ie, granulocytes, monocytes, macrophages) primarily have a phagocytic function. Granulocytes are mobile phagocytes that travel to areas of inflammation to engulf and destroy invading microorganisms. They are relatively indiscriminate in their function. Monocytes circulate, whereas macrophages are...
SjS is a chronic inflammatory disease which is in part mediated by perturbation of the glandular epithelial cells resulting in the homing of monocytes and neutrophils from blood or nearby draining lymph nodes21,41. The infiltrating monocytes differentiate into macrophages and along with neutrophils, ...
et al. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science 317, 666–670 (2007). CAS PubMed Google Scholar Geissmann, F. et al. Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids. PLoS Biol. 3, e113 (2005)....