Mast cells are classically viewed as effector cells of IgE-mediated allergic diseases. However, over the last decade our understanding has been enriched about their roles in host defense, innate and adaptive immune responses, and in homeostatic responses, angiogenesis, wound healing, tissue remodeling...
While microbes in soils, subsurfaces, and oceans of the earth gener- ally reach a density of р 108 organisms per g, the mammalian lower intestine is an extraordinarily good habitat where bacteria achieve densities of up to 1012 organisms per g contents.9 One of the most dramatic and first...
protein - a clue to the function of the eosinophil granulocyte Jonas Bystrom1*, Kawa Amin2,3, David Bishop-Bailey1 Abstract Eosinophil granulocytes reside in respiratory mucosa including lungs, in the gastro-intestinal tract, and in lymphocyte associated organs, the thymus, lymph nodes and the ...
RHOXF2, selectively expressed in the testis, was initially identified as a member of thePEPPsubfamily [15]. The humanRHOXF2gene is also named as testis homeobox gene 1 (THG1) or human paired-like homeobox protein (hPEPP2). It is located on Xq24 and contains 4 exons encoding a 288-amino...
This can result in large variations in drug metabolism by humans and often can contribute to drug–drug interactions and adverse drug reactions. Because of many of the above factors, especially CYP polymorphisms, there has been much interest in personalized medicine especially with respect to which ...
Small intestine submucosa T-tubule: Transverse tubule Google Scholar Arnold HD (1899) Weight of the “Normal” Heart in Adults. J Boston Soc Med Sci 3:174–184 PubMedPubMed CentralGoogle Scholar Dumont NA, Wang YX, Rudnicki MA (2015) Intrinsic and extrinsic mechanisms regulating satellite cell...
Glucagon-like peptide-1 (GLP-1) regulates reproduction centrally, although, the neuroanatomical basis of the process is unknown. Therefore, the putative networking of the central GLP-1 and gonadotropin-releasing hormone (GnRH) systems was addressed in male mice using whole mount immunocytochemistry and...
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of lung function to date, comprising 588,452 participants, we identified 1,020 ind
Each component was added in and slowly mixed by pipetting. The pH was adjusted to 7.4 by adding 1 N NaOH in a drop-wise fashion. All reagents were from Sigma-Aldrich unless otherwise stated. 2.3. Mass Spectrometry Sample Preparation Three batches of dECM samples from three different animals ...
In mammals, the oviduct (or the Fallopian tube in humans) can be divided into the infundibulum (responsible for oocyte pick-up), ampulla (site of fertilization), isthmus (where preimplantation embryos develop), and uterotubal junction (where embryos transit to the uterus). The oviductal fluid,...