Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have numerous shared characteristics between mice and humans. Human counterparts of mouse DC progenitors have been identified
Employee developmentNew technologyArgues that much of what has been taught in recent years on human resource management ignores the reality of globalization. Deregulation and new technology have shifted power to the employer, leaving sellers of labour competing in a buyers' market: labour is divided ...
1. Introduction: scope of this review Between 1975 and 1985, there was a rapid development of work on the development in human infants of acuity, contrast sensitivity, refraction and accommodation, and binocularity. Basic methods were established that could be applied in the clinic to assess visu...
Human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) cells were transplanted into patients suffering from macular degeneration. Medium- to long-term safety, graft survival, and possible biological activity of hESC-RPE in individuals with dry-age related macular degeneration (AMD...
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 1994; 368: 215–21. PubMed CAS Google Scholar Falk K, Rötzschke O, Stevanovié S et al. Pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide ...
We then evaluate dysbiosis in the small intestine in several human disease models, including small intestinal bacterial overgrowth, short-bowel syndrome, pouchitis, environmental enteric dysfunction, and irritable bowel syndrome. What is clear is that the bacterial biology, and mechanisms of bacteria-...
The shortage of specialized tech talent is forcing the tech function to work differently.Specifically, it must free up human capacity through automation and deploy that capacity in higher-value activities. With their needs for tech know-how so great, companies will also have to rely on outside ...
A recent finding by single-cell transcriptomic analysis revealed the immunomodulatory capacity of red blood cells throughout human development, suggesting a long-lasting immune function of immature erythrocytes in humans [16]. Nevertheless, single-cell RNA sequencing is a powerful way to resolve the ...
Third, the structure and function of association areas always change simultaneously. The development of human advanced cognitive capabilities was accompanied by pronounced modifications to connections linking association areas23 and abnormalities in these connections were reported to be associated with many ...
Structure, function and pharmacology of human itch receptor complexes Article 17 November 2021 Ligand recognition and G protein coupling of the human itch receptor MRGPRX1 Article Open access 17 August 2023 Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in ...