Condorelli, D. F., Mudo, G., Barresi, V., and Belluardo, N. (2013) Chapter 5 - Distribution and Function of Gap Junction Coupling in Cortical GABAergic Neurons. in Gap Junctions in the Brain: Physiological and Pathological Roles (Dere, E. ed.), Academic Press, San Diego. pp 69-82...
Gap Junctions and the Regulation of Cellular Functions of Stem Cells during Development and Differentiation In multicellular organisms, the role of gap junction intercellular communication (GJIC) in the regulation of cell proliferation, cell differentiation, and ... JE Trosko,CC Chang,MR Wilson,... ...
Gap-junctional communication in osteoblasts and osteocytes is well documented and seems to be essential for the integrity of bone cells, as well as for the transfer of mechanical signals of bone loading. The role of gap junction in osteoclasts is unclear, so far, but some putative roles have...
Compare/contrast the structure and function of tight junction, desmosomes, gap junction, and plasmodesmata. Cell junctions Every living being is built from cells, similar to the way an office building is made up of different rooms. If every room was isolated, ...
function in the cochlea of conditional Gjb2 knockout mice Q Yu1,2,4, Y Wang3,4, Q Chang2, J Wang2, S Gong1, H Li3 and X Lin2 Mutations in GJB2, which codes for the gap junction (GJ) protein connexin26 (Cx26), are the most common causes of human nonsyndromic hereditary ...
It will also be important to investigate whether aging and frailty are associated with changes in expression or function of connexins in the atria since gap junctions are important determinants of CV53 and mutations that impair gap junction function have previously been linked to AF54,55. ...
Gap Junction Function and Cancer Gap junctions (GJs) provide cell-to-cell communication of essential metabolites and ions. GJs allow tissues to average responses, clear waste products, and... JW Holder,E Elmore,JC Barrett - 《Cancer Research》 被引量: 553发表: 1993年 Key Connexin 43 ...
Mutations in GJB2, which codes for the gap junction protein connexin26, are the most common causes of human nonsyndromic hereditary deafness. We inoculated modified adeno-associated viral vectors into the scala media of early postnatal conditional Gjb2 knockout mice to drive exogenous connexin26 expr...
The demonstration of small gap junctions by electron microscopy and the demonstration of the gap junction protein connexin45 indicate that the muscle mass may indeed be functionally connected. The implications regarding the spread of excitation are discussed.doi:10.1080/03008880410015138...
The formation of the nervous system requires a balance between proliferation, differentiation, and migration of neural progenitors (NPs). Mutations in genes regulating development impede neurogenesis and lead to neuropsychiatric diseases, including autis