One such effector, IcsB, is critical forintracellular survival and pathogenesis, but its mechanism of action is unknown. Here, we discover that IcsB is an 18-carbon fatty acyltransferase catalysing lysine-fatty acylation. IcsB disrupted the actin cytoskeleton in eukaryotes, resulting from-fatty ...
et al. Structure, function and evolution of the mitochondrial division apparatus. Biochim. Biophys. Acta 1763, 510–521 (2006). Article CAS PubMed Google Scholar Eme, L., Spang, A., Lombard, J., Stairs, C. W. & Ettema, T. J. G. Archaea and the origin of eukaryotes. Nat. Rev....
Describe the functions of the following organelles: (a) Flagella, (b) Cell wall. (a) Describe the structure of the cytoskeleton. (b) Describe its function. Describe the functions of the following organelles: (a) Golgi complex, (b) Lysosomes. ...
intestinal barrier function, with cell growth factors playing a vital role in this process. Among these, polyamines stand out. Polyamines, widely distributed among prokaryotes and eukaryotes, including humans, are essential for many cell functions and play a crucial role in normal cell growth, prolif...
What is the primary function of a vacuole? What is the purpose of the mitochondria in a cell? 1. What is the cell membrane? 2. What does it contain? How does it function? 3. Is it prokaryotes or eukaryotes? Which of these processes begin in the cytoplasm and ends in the mitochondria...
Structure of cytoplasm Eukaryotes (contains nucleus): Animals: Consists of a cell membrane, cytoskeleton and organelles (mitochondrion, endoplasmic reticulum, golgi apparatus, centrioles, lysosomes, peroxisomes) which lie suspended in cytosol (a gelatinous liquid which fills the cytoplasm of a cell)...
In the case of actin, the filaments retain the ability to make branch points that are critical for the rigidity of the cytoskeleton by incorporating specialized branch-inducing complexes into the filament. Because it does not involve a gross rearrangement of the protein fold, the end-to-end ...
Various studies have demonstrated that the two leaflets of cellular membranes interact, potentially through so-called interdigitation between the fatty acyl groups. While the molecular mechanism underlying interleaflet coupling remains to be fully unders
In 2010, Coste and colleagues revealed a novel family of mechanically activated cation channels in eukaryotes, consisting of Piezo1 and Piezo2 channels. These have been proposed as the long-sought-after mechanosensitive cation channels in mam‑ mals. Piezo1 and Piezo2 exhibit a unique propeller-...
The elongation, termination, and recycling phases of translation in eukaryotes. Cold Spring Harb. Perspect. Biol. 4, a013706 (2012). Article PubMed PubMed Central CAS Google Scholar Pisarev, A. V. et al. The role of ABCE1 in eukaryotic posttermination ribosomal recycling. Mol. Cell 37,...