APC is a member of the anticoagulant pathway and downregulates the coagulation process through proteolytic inactivation of factors VIII/VIIIa and factors V/Va. In a factor VIIIa degradation assay, the APC-mediated inactivation of factor VIIIa is potentiated by the synergistic cofactors protein S ...
Coagulation factors concentrations were measured by the methods of one-stage coagulation assays. To evaluate the precision of the immunodepleted plasma substrate,the linear ranges of the immunodepleted plasma substrate were investigated, comparing with imported commercial products. Results The isotype of ...
Vitamin K-dependent coagulation factors undergo several post-translational modifications before the proteins are secreted into the blood as functional zymo... R Wallin,C Stanton,SM Hutson - 《Biochemical Journal》 被引量: 30发表: 1993年 Structures and Potential Roles of Oligosaccharides in Human Coag...
Functioning platelets remain in the final product, with growth factor concentrations similar to some methods employed to create platelet concentrates to enhance coagulation. Based on the ability of the HB off-line MUF procedure to concentrate circuit blood, the clinical utility of the HB device to ...
Changes of coagulation factors following H–LR. Coagulation factors 15 min after H–LR, % 6 h after H–LR,% II 58 ± 2 67 ± 3 V 65 ± 11 69 ± 5 VII 59 ± 3 57 ± 3 VIII 51 ± 12 66 ± 11 IX 41 ± 5 54 ± 6 X 60 ± 7 62 ± 6 XI 33 ± 6 37 ± 5 XII ...
Interactions between tissue factor and factor VIIa are the primary initiators of coagulation in hemostasis and certain thrombotic diseases. Tissue factor, an integral membrane protein expressed extensively outside of the vasculature, is the regulatory protein cofactor for coagulation factor VIIa. Factor VI...
04止血与凝血功能的检查(04 hemostasis and coagulation function test).doc,04止血与凝血功能的检查(04 hemostasis and coagulation function test) Clinical Laboratory Manual The fourth chapter is the examination of hemostasis and coagulation function Index:
liver is found in the superior right quadrant of the abdomen and weighs approximately 1.5 kilograms. Its main functions are detoxification, metabolism, nutrient storage (e.g., iron and vitamins), synthesis of coagulation factors, formation of bile, filtration, and storage of blood.Liver: Anatomy:...
O-glucosylation refers to the addition of glucose (Glc) to EGF-like repeats of diverse substrates, such as coagulation factors VII, IX and protein Z7, Notch receptor and its ligands8, crumbs29, Eyes shut (Eys) ofDrosophila10, etc., some of which have shown impaired function after an aber...
Analysis of factors of abnormal coagulation and platelet function in patients with non-small cell lung cancerChangxing People's Hospital Abstract: Objective To analyze the factors of abnormal coagulation and platelet function in patients with non-small cell lung cancer. Methods Three hundred and ...