Cells in this zone are arranged in long anastomosing cords or columns, separated by small capillaries. They are responsible for the secretion of glucocorticoid hormones (e.g., corticosterone or cortisol), which promote the elevation of blood glucose in addition to many other effects. The ...
However, microscopic changes in the small arterioles with collapsed capillaries and endothelial cell degeneration in heart and skeletal muscles are also noted [238]. Collectively, these findings implicate collagen XVIII as a negative regulator of angiogenesis and as an anti-atherosclerotic factor. ...
ANP induces hypovolemia and decreases blood pressure (BP). ANP lowers BP with increased permeability of capillaries and fluid efflux from blood [69]. ANP decreases cardiac load by shifting intravascular fluid into interstitial space. ANP stimulates Ca2+/calmodulin-dependent endothelial nitric oxide (NO...
depending on its location in the body. It does not have any blood vessels within it (i.e., it is avascular). Skin that has four layers of cells is referred to as “thin skin.” From deep to superficial, these layers are the stratum basale, stratum...
ultimately leading to the enhanced browning of subcutaneous adipose tissue thereby ameliorating obesity outcomes [245,246]. LXRs also show neuroprotective roles in different experimental stroke models: stabilizing the integrity of brain capillaries, improving stroke outcome, and suppressing neuro-inflammation;...
In our previous report, we also demonstrated that human ASCs injected intra-arterially protected against the loss of peritubular capillaries following AKI [15]. It is possible that ASC-CS also has a similar protective effect on vascular damage since Ang-2 levels, which have been shown to corre...
After incubation for 10 min at 4 °C, the samples were centrifuged at 14,000 g for 4 min and loaded into MST premium capillaries (NanoTemper). Measurements were performed with various LED power. Data analyses were performed using the NanoTemper analysis software. RNA in situ hybridization. ...
The BBB is a unique functional structure found at the level of brain arterioles and capillaries, which is formed by brain microvascular endothelial cells (BMEC) connected by extensive tight junctions, with limited trans- and para-cellular transport, compared to endothelial barriers elsewhere in the ...
The aqueous solutions were injected into the interaction vacuum chamber through 25–30 μm orifice diameter glass capillaries at the tip of a LJ rod assembly. The liquid flow rate was 0.5–0.8 ml min−1. In the EASI experiments, the temperature was stabilized to 10 °C by water-cooling ...
In brief, glomeruli were scored from 0–6, with 0 being no observed lesions, 1–2 mild lesions with mesangial deposits and/or hypercellularity, 3–4 moderate to severe lesions with mesangioproliferation, wire-loop capillaries and/ or fibrous necrosis of capillary loops, intraglomerular crescent ...