Astrocytes are the major glial cell within the central nervous system (CNS) and have a number of important physiological properties related to CNS homeostasis. The aspect of astrocyte biology addressed in this review article is the astrocyte as an immunocompetent cell within the brain. The capacity...
the long, slender projection of a neuron that conductselectrical impulses. They also control neurotransmitters, chemicals that enable the transfer of electrical signals throughout the brain and nervous system. In addition, astrocytes build the blood-brain...
Astrocytes are abundant glial cells in the central nervous system (CNS) that perform diverse functions in health and disease. Astrocyte dysfunction is found in numerous diseases, including multiple sclerosis, Alzheimer disease, Parkinson disease, Hunting
Inducible ablation of astrocytes shows that these cells are required for neuronal survival in the adult brain Glia, 34 (4) (2001), pp. 272-282 Google Scholar [15] R. Niranjan The role of inflammatory and oxidative stress mechanisms in the pathogenesis of Parkinson's disease: focus on astrocy...
How astrocytes grow and integrate into neural circuits remains poorly defined. Zebrafish are well suited for such investigations, but bona fide astrocytes have not been described in this system. Here we characterize a zebrafish cell type that is remarkab
The main elements of the central nervous system are the brain and the spinal cord. It contains millions of neurons and glial : astrocytes, oligodendrocytes, and microglia. The main role of the CNS is to process information, analyze signals, and activate effector organs. The role of the glial...
Astrocytes provide support for neurons, regulate metabolic processes, and influence neuronal communication in a variety of ways, including through the homeostatic regulation of glutamate. Following 2-h cocaine or methamphetamine self-adm... B Siemsen,C Reichel,K Leong,... - 《Neuroscience》 被引量...
Pretty much everything happening in the brain would fail without astrocytes. These star-shaped glial cells are known to have a critical role in synapse creation, nervous tissue repair, and the formation of the blood-brain barrier. But while we have decad
▲ Neurons (green), astrocytes (red), and cell nuclei (blue) in the brains of pigs. On left, brain tissue left untreated for 10 hours after death; right, brain tissue subjected to the experiment. Those that received the control solution turned within hours to what researchers described as ...
glial cells are classified as follows: (1) microglia, the only glial cells of immune origin, which reach the brain through the blood during early development; (2) astrocytes; and (3) Schwann cells and oligodendrocytes, which form myelin layers around axons in the peripheral and central nervous...