From time to time, for many years, anatomists, embryologists and pathologists have been discovering and rediscovering the fact that fatty adipose tissue is not merely a common connective tissue loaded with stored simple fats, but, to a large extent, is structurally, developmentally and ...
One of the earliest reports of adipose tissue was made by the Swiss naturalist Conrad Gessner in 1551 (as translated by Cannon and Nedergaard [1]). However, the notion that adipose tissue was composed of living lipid-laden cells was hotly debated [2]. The past decades have seen a remarkabl...
In health, PVAT secretes anti-contractile factors that relax the underlying artery. PVAT’s contributions to vascular function include more than production of vasoactive substances. We hypothesized that PVAT benefits the artery by assisting the function
In this critical review, we highlight new developments in the special class of microfluidic systems aimed at culture and interrogation of adipose tissue, a sub-field of microfluidics that we contend is only in its infancy. We close by reflecting on these studies as we forecast a promising ...
Furthermore, both lipolytic activity in the perirenal fat tissue and specific GDP binding in brown adipose tissue mitochondria, as the biological index of... Kobayashi*, Yoshinori,Y Nakano,M Kizaki,... - 《Planta Medica》 被引量: 356发表: 2001年 Modulation of gene expression in hibernating...
Targeting the JAK-STAT pathway may be a novel therapeutic approach for the treatment of obesity and related metabolic disorders. 展开 关键词: Adaptive thermogenesis Brown adipose tissue Diabetes Glucose homeostasis Janus kinase 2 (JAK2) Obesity Uncoupling protein 1 (UCP1) DOI: 10.1007/s00125-015-...
Mesenchymal stem cells (MSCs) are multipotent progenitors derived from tissue stroma that differentiate into adipocytes, chondrocytes and osteoblasts when expandedin vitro. Although the properties of the in vitro-expanded progeny are well defined, the in
interest in the contributions of resident cells in nerves, Schwann cells (SCs), and endoneurial mesenchymal cells, as well as the nonclassical functions of peripheral nerves, such as the regulation of homeostasis,9,10,11,12effects on development,13,14and roles in tissue regeneration.15,16,17,...
Taking into account the sexual dimorphism previously reported regarding mitochondrial function and biogenesis in brown adipose tissue, the aim of the present study was to go further into these differences by investigating the effect of ovariectomy and 17-β estradiol (E2) replacement on brown adipose ...
Intestinal epithelial cells (IECs) provide a physical and biochemical barrier that segregates host tissue and commensal bacteria to maintain intestinal homeostasis. Secretory IECs support this function through the secretion of mucins and antimicrobial peptides. IECs maintain specialized pathways for the deli...