Alanine racemase (Alr) is a bacterial enzyme that catalyses the conversion of L-alanine to D-alanine (D-Ala)1. This function is critical for the growth of bacteria due to their need for D-alanine, an essential component in the biosynthesis of cell wall peptidoglycan in both gram-positive ...
Cancer cells are under chronic endoplasmic reticulum (ER) stress due to hypoxia, low levels of nutrients, and a high metabolic demand for proliferation. To survive, they constitutively activate the unfolded protein response (UPR). The inositol-requiring protein 1 (IRE1) and protein kinase RNA-lik...
The data suggest lysosomes play a key role in the maintenance of stem cell activity. However, the lysosomal morphology and function of O-ADSCs is less investigated. In the present study, we will first compare the biological activity of L-ADSCs and O-ADSCs and focus on investigating the ...
Newly designed 16S rRNA metabarcoding primers amplify diverse and novel archaeal taxa from the environment. High-throughput studies of microbial communities suggest that Archaea are a widespread component of microbial diversity in various ecosystems. However, pro... Mohammad,Bahram,Sten,... - 《Environ...
Oxidation Resistance 1 (OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, antioxidant pathways, cell cycle, neuronal protection, a
The reaction mixture of 20 µL contained 1 × SsoAdvanced SYBR Green Supermix (Bio-Rad), 250 nM of each primer (Sigma Aldrich) and 1 µL of cDNA (100 ng/µL); control without template (NTC, blank) was included in each assay. The thermal cycling conditions are ...
Trypsin-like serine proteases are involved in a large number of processes including digestive degradation, regulation of developmental processes, yolk degradation and yolk degradome activation. Trypsin like peptidases considered to be involved in digesti
crescentus responds to exposure to various heavy metals by altering the expression of a large number of genes. Results In this work, we show that the ECF sigma factor σF is one of the regulatory proteins involved in the control of the transcriptional response to chromium and cadmium. ...
Inflammatory microenvironment causes the change of epigenetic modification in periodontal ligament stem cells derived from periodontitis tissues (P-PDLSCs), which results in defective osteogenic differentiation compared to cells from healthy tissues. It’s urgent to explore therapeutic strategies aimed at epi...
Sweet maize and popcorn retain tillering growth habit during maize diversification. However, the underlying molecular genetic mechanism remains unknown. Here, we show that the retention of maize tillering is controlled by a major quantitative trait locus