Inhalation therapy provides rapid clinical responses, leading to immediate control of the disease. It has been widely used for a long time for treating COPD and asthma, with inhaled bronchodilators and glucocorticoids being the cornerstones of treatment. The efficacy of inhalation therapy is associated...
WTC-AHRwill be defined as having a positive methacholine (PC200 < 16), or a positive bronchodilator response (by ATS/ERS guidelines with improvement of FEV1by 12% and at least 200 mL) at least once post-9/11 [73,74] and/or EMR diagnosis.GERDwill be defined as: biopsy-proven ero...
Chronic obstructive pulmonary disease (COPD) is underdiagnosed with the current gold standard measure pulmonary function test (PFT). A more sensitive and simple option for early detection and severity evaluation of COPD could benefit practitioners and patients. Methods In this multicenter retrospective stu...
Spirometry was performed without bronchodilator. Only tests from subjects with complete datasets that fulfilled the criteria for quality and acceptability were included. All PFTs were conducted in the same laboratory using Jaeger Master Screen Body (Eric Jaeger, Würzburg, Germany). Experienced ...
Each mouse underwent pulmonary function testing before euthanasia with Buxco-PFT (PFT, DSI Harvard Bioscience, New Brighton). FinePoint software (DSI Harvard Bioscience, New Brighton) was used to record relevant parameters. In the INCB3284 treatment experiment, all mice were divided into three ...
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Secondary end-point outcomes were consistent with those of the co-primary end points. These data, together with those from the wider phase III clinical program, provide evidence for the 24-h bronchodilator efficacy of olodaterol QD in this patient population....
In cases where multiple measurements were reported for each value (i.e. pre- and post- bronchodilator treatment), the greatest measurement was used for the analysis. Observed measurements and percentage of standard values based on age, sex, height, and weight were included for analysis. The ...
Based on pulmonary function testing (PFT), obstructive lung disease may be observed in 16% of children and 8% of adults with SCD, while restrictive lung disease may be seen in up to 28% of adults and only 7% of children with SCD [34, 35]. Sleep-disordered breathing, which can ...
Our objectives were to determine the causes of acute respiratory failure (ARF) in elderly patients and to assess the accuracy of the initial diagnosis by the emergency physician, and that of the prognosis. In this prospective observational study, patient