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Semaphorins are secreted, transmembrane, and GPI-linked proteins, defined by cysteine-rich semaphorin protein domains, that have important roles in a variety of tissues. Humans have 20 semaphorins,Drosophilahas five, and two are known from DNA viruses; semaphorins are also found in nematodes and cr...
Right censoring of this outcome (i.e. when the exact time of an event is unknown for some patient, which should be considered in the statistical model) was considered because AD is a degenerative condition, meaning that all patients would probably convert, even if it occurs after the end of...
A detailed understanding of the genetic basis of cancer is of great interest to public health monitoring programs. Although many studies have been conducted in Brazil, a global view on the molecular profile related to hereditary breast and ovarian cancer
(Fig.5C). These changes in NRXN, NGL, SEMA6, NEGR, and EPHA signaling were ML-specific meaning signaling from these pathways was undetectable in the MH and FL mature oligodendrocytes (Fig.5C). Similarly, increased prosaposin (PSAP) signaling was specific to MH and FL compared to ML ...
Bile acids (BAs) are steroid-derived molecules with important roles in digestion, the maintenance of host metabolism, and immunomodulation. Primary BAs are synthesized by the host, while secondary BAs are produced by the gut microbiome through transforma
Purpose in Life Test – Short Form which assesses a person’s perceived meaning and purpose in life. The scale contains 4 items measuring presence of goals, goal completion and meaning in life. Responses are on a Likert scale ranging from 1–7 with a total score ranging from 4 to 28. Hi...
This is a quadruple-blinded study; meaning that participants, care providers, investigators, and outcome assessors are blinded to the assigned intervention. Furthermore, data analysts and the independent safety monitoring committee will be blinded. Nutritional intervention will be blinded and marked with...
[53]. Municipalities have no legislative power, and they stand solely as an administrative body. They represent self-governing bodies, meaning that they act independently from the federal state and federal provinces in some fields. Districts are groups of municipalities and in charge of the ...
Gold/silver bimetallic nanoparticles still attract extensive interest due to their favorable properties e.g. in plasmonics or catalysis. We present here a facile and robust way for the production of clean Au/Ag binary nanoparticles (BNPs) with a total co