can be accessed and used by as many individuals as reasonably feasible, without requiring any specialized design or adaptations.’ Inclusive design is a concept that is used similarly to universal design and refers to a more comprehensive ‘design for all’ meaning, including spaces and services. ...
This prescription exhibited effects via multi-link comprehensive treatment for COVID-19 and significantly shortened the time of recovery (meaning, nucleic acid test turning negative), hospital stay, and improved clinical symptoms including physical and chemical examinations and CT results of the lung. ...
Epigenomic changes, that are responded to environment stimulate and reflect in phenotypic changes, provide another meaning of the “molecular phenotype” definition. Recent advances in population epigenomics studied the association between genetic SNPs and epigenomic variations in a global accession collection...
main differences in brain development between the sexes happen during the prenatal period and are largely determined by the differential expression of genes on the sex chromosomes, although many other genes on autosomes may also contribute. Furthermore, in some genes the exons show sex-specific patte...
AKT, or protein kinase B, is a central node of the PI3K signaling pathway that is pivotal for a range of normal cellular physiologies that also underlie several pathological conditions, including inflammatory and autoimmune diseases, overgrowth syndromes
In this context, we explore the problem of mapping reads on a graph. Aligning or mapping sequences on sequence graphs (a generic term meaning a graph representing sequences along its paths) has already been explored in the literature in different application contexts: assembly, read correction, ...
whether clinically applicable or clinically absurd. The clinical applicability and meaning of the c-index has been questioned recently [6]. Modelgoodness of fittests are often presented with the model development and validation, but these tests do not indicate how well a model predicts patient outco...
This kind of protein has been found in pluricellular eukaryotes but not in yeast and binds directly to RNase L to prevent it from binding 5'-phosphorylated 2',5'-linked oligo-adenylates [34]. The biological role of ABC and the meaning of its up-regulation at the level of transcript in...
Variant consequences are described using a standardized set of variant annotation terms [67] which were defined in collaboration with the Sequence Ontology (SO) [68]. Each consequence term has a stable identifier and definition, thereby removing ambiguity in definition or meaning. Structuring the cons...
The Internet of Things (IoT) has been rapidly evolving towards making a greater impact on everyday life to large industrial systems. Unfortunately, this has attracted the attention of cybercriminals who made IoT a target of malicious activities, opening