The cartilage in the articular cartilage does not have the ability to regenerate, meaning that damage to the tissue cannot heal [31]. Meanwhile, traditional cartilage repair treatments do not achieve long-term function, rarely restoring the tissue to its original state, resulting in poor treatment ...
Novel cancer biomarkers are urgently needed, not least as integrated components of precision and personalized medicine [54]. Several purposes of biomarkers can be envisioned: 1) diagnosis, or detection of cancers, from early to recurrent; 2) prognosis, to anticipate the likely course of disease; ...
The average NSRs of the healthy controls of the ankle and hip joint angle and of the ankle and hip torque were 0.24 and 0.28, 0.56 and 0.35, respectively. This results in an average NSR of 0.36, meaning that about 74% (i.e., 1/(1+0.36)) of the response is captured by the estim...
” example by Kanerva [47]. Hypervectors typically represent information holographically, meaning that each of the thousands of dimensions contains the same amount of information
, resveratrol, α- lipoic acid, and rutin, papaverine, citrulline, resveratrol, and α-lipoic acid had moderate clearance rates, indicating that these compounds have a reasonable elimination time in the body. Additionally, alprostadil, L-arginine, and rutin had lower clearance rates, meaning ...
This kind of protein has been found in pluricellular eukaryotes but not in yeast and binds directly to RNase L to prevent it from binding 5'-phosphorylated 2',5'-linked oligo-adenylates [34]. The biological role of ABC and the meaning of its up-regulation at the level of transcript in...
Apart from Opisthokonta and Amoebozoa, two sequences were found in the Plantae databases, but their meaning is not clear. Thus, it appears that the distribution of the tCWCH2 sequence motif is essentially limited to the Uniconta (a collective term for the Opisthokonta and Amoebozoa super...
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended, including statements about the intended use of proceeds of the offering. The words “may,”“will,”“could,”“would,”“shoul...
responded strongly in cultures with dual stress compared with cultures only heated or induced [100]. In particular, genes coding for RNA polymerase likerpoA/Sand ribosome coding genes were downregulated, meaning that transcription and translation probably diminished. Moreover, genes associated to the py...
All analyses were conducted on an intent-to-treat basis, meaning that data were analyzed by the treatment groups to which patients were randomly assigned, even if the patient did not take the assigned treatment, did not receive the correct treatment, or did not comply with the protocol. No ...