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7]. In most cases, spacer addition was observed at the beginning, the ‘leader’ end, of the array [1] and the pattern in metagenomic samples suggest that deletion
The rest of the paper presents the background in “Background” section and related work in “Related work” section. Mathematical modeling and formal description are articulated in “Mathematical modeling and formal description” section. The proposed framework is detailed in “Proposed model” sectio...
While some of the differentially expressed genes (DEGs) and TFs may be known to functionally interact, it is expected that many interactions are implied, meaning the interaction is not verified experimentally and weakly supported in the literature. Therefore, there is a growing need to develop new...
Further review of the BACs showed that the 13 groups containing MPRE20 and MPRE57 sometimes occurred in overlapping regions between pairs of clones in the BAC collection, meaning that we only had 7 unique loci plus one very unique locus that had a PRE1a (Porcine Repeat Element 1a, as identi...
At present, without more in-depth analyses concerning the extent to which the pln1 cluster may be conserved across bees, we can only speculate on the possible meaning of this architectural genomic conservation. The collection of pollen, which underlies the pollen hoarding syndrome in A. mellifera...
and computing conjfdr statistics. the conjfdr is given as the maximum value between the conditional fdrs (condfdr) of two given conditions. the method is not affected by the direction of the allele effects [40,41]. to ensure the results were comparable, we analyzed a common set of 5,264...
Precision medicine is a promising approach that has revolutionized disease prevention and individualized treatment. The DELFOS oracle is a model-driven genomics platform that aids clinicians in identifying relevant variations that are associated with dis
Biological function of identified variables Finally, we report the biological meaning of variables identified using all data. Many of the identified SNP and CpG markers had functions that are related to the regulation of the circulating level of TG, which is a major storage molecule for metabolic ...
We also report the availability of Datgan (Welsh, meaning 'to express'), the suite of scripts that was used to construct both the underlying data tables and the web interface that form GDP. Datgan was written in the python language. It is packaged as a reusable software system for constru...