Epigenomic changes, that are responded to environment stimulate and reflect in phenotypic changes, provide another meaning of the “molecular phenotype” definition. Recent advances in population epigenomics studied the association between genetic SNPs and epigenomic variations in a global accession collection...
Epigenomic changes, that are responded to environment stimulate and reflect in phenotypic changes, provide another meaning of the “molecular phenotype” definition. Recent advances in population epigenomics studied the association between genetic SNPs and epigenomic variations in a global accession collection...
The term activity-based protein profiling (ABPP) has been generalized to any kind of pulldowns featuring some covalent bond between the small molecule of interest and the proteins it is bound to. This wording was meaningful when it was coined for the study of hydrolases: the probe was effecti...
The decision to use the BRIEF-A Self-Report was partially driven by the recognition that demonstrations of improved cognitive function on laboratory-based measures have limited practical meaning if patients are unaware of improvement in their everyday lives. Thus, a self-report provides some degree ...
The decision to use the BRIEF-A Self-Report was partially driven by the recognition that demonstrations of improved cognitive function on laboratory-based measures have limited practical meaning if patients are unaware of improvement in their everyday lives. Thus, a self-report provides some degree ...
As an example, a hypothetical "gene2" would be annotated with the gene description, gene2:chordates:80,55:1-1:5:3,4:TS, meaning that gene2 has orthology only within chordates with, respectively, 80% and 55% overall protein and nucleotide identity (alternatively, dN and dS can be used)...
One concern with all of the studies we collectively do in our mouse models of AD pathology is that they are kept in relatively sterile conditions (e.g., specific pathogen free housing), meaning that they are subject to limited immune priming [58,59]. Herein, we explored how immune priming...
FISH using site-specific DNA probes (YACs, BACs, PACs, cosmids) is usually used to map chromosomal regions, within which a breakpoint is located [3,5,13,61]. Additionally, these probes can be used for diagnosing known microdeletion and microduplication syndromes [1,3,13,27], aneuploidy an...
The limitations of traditional computer-aided detection (CAD) systems for mammography, the extreme importance of early detection of breast cancer and the high impact of the false diagnosis of patients drive researchers to investigate deep learning (DL) methods for mammograms (MGs). Recent breakthroughs...
Because of this government policy, bikers enjoy a sort of encouraged state of privilege(特权), meaning they will stick to this means of transportation even during the coldest winter season. Danes' tendency toward a healthy and environmentally friendly lifestyle also lends itself to choosing cycling...