This could serve as a strong indication of these organisms trying to adjust to the environmental stress because the pgaA and pgaB are responsible for transporting the PGA essential in the movement of adhesin out of the periplasm to form the biofilm. Also, the LsrK is responsible for ...
Self-directed violence (SDV) comprises both suicide and self-injury and represents a pressing problem among incarcerated persons. Negative impacts of SDV in correctional settings also extend to behavioral health clinicians (BHCs) (e.g., job turnover). Co
type of patient, we plotted the log2FC for every KO whose abundance significantly changed after transplant, either increasing (Fig.6C) or decreasing (Fig.6D). The dynamics of the abundance for each single KO analyzed followed the same trend in both groups of patients, independently on future ...
Current best practices in single-cell RNA-seq analysis: A tutorial. Mol Syst Biol. 2019;15(6). https://doi.org/10.15252/msb.20188746. Wagner C, Griesel M, Mikolajewska A, Mueller A, Nothacker M, Kley K, Metzendorf M-I, Fischer A-L, Kopp M, Stegemann M, et al. Systemic ...
Accelerated biological aging has been verified to be a critical risk factor for a number of age-related diseases, but its role in dementia remained unclear. Whether it modified the effects of genetic factors was also unknown. This study evaluated the associations between accelerated biological aging...
At the start of the trial, the coordinating center will conduct a tutorial on the web-based data entry system. Overall quality and completeness of the data will be checked every six months. Plans for communicating important protocol amendments to relevant parties (e.g., trial participants, ethic...
Other parameters which further tune the structure of the trees and forest have been left at their default values, and the code for the SpRF model is based on a tutorial from the method's authors [62]. FRK Fixed Rank Kriging (FRK) [48] is a spatio-temporal modelling framework built for...
Correction: clinical validation of full HR-HPV genotyping HPV Selfy assay according to the international guidelines for HPV test requirements for cervical cancer screening on clinician-collected and self-collected samples. J Transl Med. 2023;21(1):49. https://doi.org/10.1186/s12967-023-03882-5....
Human visceral leishmaniasis (VL) is a systemic disease with high case-fatality rates and a widespread distribution. Continuous evaluation of the risk factors for VL is essential to ensure the effective implementation of prevention and control measures.
Another important contribution of our tutorial is that we cover the recent trend of using machine learning (ML) for causal inference such as targeted minimum loss-based estimation (TMLE) and double machine learning (DML) [10,11,12]. As these tools are now widely used in applied data analyse...