influencing the onset, symptoms, progression, and treatment outcomes of various diseases (Fig.1). Females exhibit higher susceptibility to autoimmune diseases such as Sjögren syndrome (SS), systemic lupus erythematosus (SLE), hypothyroidism (HT), rheumatoid arthritis (RA), Graves' disease (GD), ...
The symptoms of an immediate post-injection reaction may overlap with those of anaphylaxis; prompt identification of anaphylaxis is important to avoid a delay in treatment. In general, symptoms of an immediate post-injection reaction have onset several months after the initiation of treatment, ...
Clinical gynecologist experts were present to ensure the item concepts were accurate and relevant and that no clinically important symptoms or functional interference were missed (authors FX, YY, and XGZ). The researchers and clinicians jointly agreed on the final list of symptoms. In screenshots of...
Mechanism of TH intracellular action. The introduction of TH into the cell is mediated by transporters. T4 can be converted into T3 by the enzyme, DIO2. DIO1 is also involved in the conversion of T4 (not shown in the figure). T3 and T4 bind to the THRs mainly associated with RXR, an...
systematic medical diagnoses that are applicable to all medical specialties. For example, common medical prefixes, morphemes, and suffixes give rise to o = ’hypothyroidism’, o = ’tachycardia’, and o = ’hypophagocytosis’. The formula scales well with the developments in clinical...
In addition to its recognized role in providing structural support, bone plays a crucial role in maintaining the functionality and balance of various organs by secreting specific cytokines (also known as osteokines). This reciprocal influence extends to
We have therefore decided to focus on a list of phenotypes that can be caused by rare and non-rare diseases. In endocrinology, this resulted in the symptom complex hyper- and hypothyroidism with various diseases, some of which are rare (e.g. TSH-oma, thyroid receptor resistance), while ...
The assessment of symptoms was performed by applying Mann–Whitney U test of significance. Results: After eradication therapy, average BMI was increased from pretreatment values of 23.24 ± 2.1 to 26.4 ± 3.8 kg/m2 (p = 0.028). Also a significant different in body weight was observed from ...
In this study, we report novel relationships between GDF11 and disease, namely asthma and hypothyroidism, in contrast to its formerly assumed role as a rejuvenating factor in basic aging and cardiovascular health. We propose that these associations are mediated through the involvement of GDF11 in ...
The Wall Street Journal reported the suppression of the results of a trial comparing the bioavailability of generic and brand-name levothyroxine products in the treatment of hypothyroidism; the investigators had concluded that the products were bioequivalent and in most cases interchangeable [116,117]....