The proportion of the population aged 65 years and older is predicted to rise from 13.50% (2020) to 35% (2050) [4, 5], which has aroused great public concern. Maintaining a regular lifestyle and good health has become an important issue for older adults owing to economic growth and ...
figcaption>\n \n \n \n <blockquote class=\"content\">\n Five years ago, Nikole Hannah-Jones launched, her "1619 Project," a series of essays in The New York Times that argued the practice of slavery is the true foundation of America. She won a Pulitzer prize, the projec...
For example, The Cancer Genome Atlas (TCGA), an influential cancer genomics project that aggregates an array of data, including mRNA, DNA methylation, miRNA expression, and mutation information, spanning over 30 cancer types and a multitude of patient cases [2]. Unlike single-omics datasets, ...
6j, k). In conclusion, these findings indicate that PGG exerts a protective effect against AILI by inhibiting the activation of the cGAS-STING pathway in an AILI model. Discussion Excessive acetaminophen intake leading to acute liver damage is a prevalent public health issue worldwide and requires...
Therefore, the issue of frailty has received considerable attention among older people due to mounting evidence showed that it could lead to serious consequences for their physical and psychological health [5], finally increasing the risk of mortality [6, 7]. Although ageing is strongly associated ...
Through transplantation of fecal bacteria from the HFD mice to the mice on a normal diet, we confirmed that gut microbiota dysbiosis contributed to HFD-induced deteriorated fertility and disrupted estradiol synthesis. Utilizing untargeted and targeted metabolomics analyses, we identified L-saccharopine as...
Gene expression studies are an important tool in biological and biomedical research. The signal carried in expression profiles helps derive signatures for the prediction, diagnosis and prognosis of different diseases. Data science and specifically machin
In that context, the project networkNiddaManaimed at comprehensively investigating the ecosystem health of a highly anthropogenically influenced river system in Central Hesse, Germany, and at identifying potential key factors of pollution to support and advise authorities in their effort to improve the ...
The increasing availability of quantitative data on the human brain is opening new avenues to study neural function and dysfunction, thus bringing us closer and closer to the implementation of digital twin applications for personalized medicine. Here we
While the chemistry of artists’ paints has previously been studied and reviewed, these studies only capture a portion of the properties affecting the response of paint materials. The mechanical properties of artists’ paints relate to the deformation re