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A specialized nanoemulsion of curcumin is better than conventional solution form drugs in enhancing the efficiency of drug delivery into the cells, down-regulating Pgp expression, inhibiting the NFκB pathway and promoting apoptotic response [68, 77]. Active ingredients - others Schizandrins, the ...
d Western blot analysis shows expression of cathepsin B in both mature and pro form while cathepsin L only in the pro form. The cleavage of PLG in this tumor cell line is predominantly due to CtB. e, f Anatomical image and GluCEST map from a rat brain with a 9L tumor. g At 60 ...
Basic leucine zipper (bZIP) transcription factor gene family is one of the largest and most diverse families in plants. Current studies have shown that the bZIP proteins regulate numerous growth and developmental processes and biotic and abiotic stress r
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In addition to biosynthesis pathways, a full comprehension of secondary metabolism must also take into account the transport and subcellular compartmentalization of substances. Here, we examined the MATE (Multidrug and Toxic Compound Extrusion, or Multi-Antimicrobial Extrusion) gene family in the tomato ...
An interview study from the National Center for Health Statistics with over 31,000 participants indicated that 36% of American adults had used some form of CAM therapy (self- or practitioner-provided) during the last 12 months [18]. The forms and methods of integration of CAM and WM are ...
The large-scale identification of physical protein-protein interactions (PPIs) is an important step toward understanding how biological networks evolve and generate emergent phenotypes. However, experimental identification of PPIs is a laborious and erro
The therapeutic targets of OA were converted from “gene name” to “UniProtKB” form using the UniProt database (https://www.uniprot.org) [36]. Next, the KEGG IDs were obtained, and the target’s pathway information was matched using KEGG Mapper (https://www.genome.jp/kegg/mapper/). ...
The processing mechanisms mainly include the following aspects: (i) directly reducing contents of toxic constituents; (ii) structural transformation of constituents; (iii) improving solubility of constituents; (iv) physically changing the existing form of constituents; (v) and influence by excipients. ...